Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process
The introduction of 3D bioprinting first begin in the late 20th century and it has become a rapidly emerging technology, widely recognised around the world for its capability to fabricate living organ for transplantation, prosthetics and 3D tissue models for drug testing. In 3D bioprinting, it incor...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/139224 |
| _version_ | 1811679784153907200 |
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| author | Lee, Kai Theng |
| author2 | Chan Wai Lee |
| author_facet | Chan Wai Lee Lee, Kai Theng |
| author_sort | Lee, Kai Theng |
| collection | NTU |
| description | The introduction of 3D bioprinting first begin in the late 20th century and it has become a rapidly emerging technology, widely recognised around the world for its capability to fabricate living organ for transplantation, prosthetics and 3D tissue models for drug testing. In 3D bioprinting, it incorporates the use of bio-ink made up of several living cells combined with its compatible base into different printing technique to fabricate a biomedical structure that mimic the characteristic of natural tissue. However, the difficulties faced during the process of bioprinting lies with the ability to retain the biological and physical properties of these living cells before, during and after printing. In this project, a 2D Computational Fluid Dynamic simulation was conducted using an overset meshing technique to analyse the stresses experienced by an alginate gel particle immersed in a fluid stream of different viscosity. Additionally, based on the relevant stresses obtain, a demonstration of an uncoupled fluid-structure interaction over a deformable body will be carried out using ABAQUS. The investigation of particle deformation in microfluidic constrictions is relevant to also serve as a model to understand the biological phenomena, for instance, the behaviour of the red blood cells when it is moving through a narrow blood vessel. |
| first_indexed | 2024-10-01T03:14:39Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/139224 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:14:39Z |
| publishDate | 2020 |
| publisher | Nanyang Technological University |
| record_format | dspace |
| spelling | ntu-10356/1392242023-03-04T19:38:36Z Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process Lee, Kai Theng Chan Wai Lee School of Mechanical and Aerospace Engineering chan.wl@ntu.edu.sg Engineering::Mechanical engineering::Fluid mechanics Engineering::Mathematics and analysis::Simulations The introduction of 3D bioprinting first begin in the late 20th century and it has become a rapidly emerging technology, widely recognised around the world for its capability to fabricate living organ for transplantation, prosthetics and 3D tissue models for drug testing. In 3D bioprinting, it incorporates the use of bio-ink made up of several living cells combined with its compatible base into different printing technique to fabricate a biomedical structure that mimic the characteristic of natural tissue. However, the difficulties faced during the process of bioprinting lies with the ability to retain the biological and physical properties of these living cells before, during and after printing. In this project, a 2D Computational Fluid Dynamic simulation was conducted using an overset meshing technique to analyse the stresses experienced by an alginate gel particle immersed in a fluid stream of different viscosity. Additionally, based on the relevant stresses obtain, a demonstration of an uncoupled fluid-structure interaction over a deformable body will be carried out using ABAQUS. The investigation of particle deformation in microfluidic constrictions is relevant to also serve as a model to understand the biological phenomena, for instance, the behaviour of the red blood cells when it is moving through a narrow blood vessel. Bachelor of Engineering (Mechanical Engineering) 2020-05-18T05:54:20Z 2020-05-18T05:54:20Z 2020 Final Year Project (FYP) https://hdl.handle.net/10356/139224 en B314 application/pdf Nanyang Technological University |
| spellingShingle | Engineering::Mechanical engineering::Fluid mechanics Engineering::Mathematics and analysis::Simulations Lee, Kai Theng Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process |
| title | Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process |
| title_full | Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process |
| title_fullStr | Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process |
| title_full_unstemmed | Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process |
| title_short | Computational fluid dynamic simulation of the non-newtonian flow in a 3D printing process |
| title_sort | computational fluid dynamic simulation of the non newtonian flow in a 3d printing process |
| topic | Engineering::Mechanical engineering::Fluid mechanics Engineering::Mathematics and analysis::Simulations |
| url | https://hdl.handle.net/10356/139224 |
| work_keys_str_mv | AT leekaitheng computationalfluiddynamicsimulationofthenonnewtonianflowina3dprintingprocess |