Enriched expression of neutral sphingomyelinase 2 in the striatum is essential for regulation of lipid raft content and motor coordination
Sphingomyelinases are a family of enzymes that hydrolyze sphingomyelin to generate phosphocholine and ceramide. The brain distribution and function of neutral sphingomyelinase 2 (nSMase2) were elucidated in this study. nSMase2 mRNA expression was greatest in the striatum, followed by the prefrontal...
Main Authors: | Tan, Laura Hui-Ru, Tan, Angela Jin-Rong, Ng, Yu-Ying, Chua, John Jia-En, Chew, Wee-Siong, Muralidharan, Sneha, Torta, Federico, Dutta, Bamaprasad, Sze, Siu Kwan, Herr, Deron R., Ong, Wei-Yi |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/139285 |
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