Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering

The cell surface serves important functions such as the regulation of cell-cell and cell-environment interactions. The understanding and manipulation of the cell surface is important for a wide range of fundamental studies of cellular behavior and for biotechnological and medical applications. With...

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Main Authors: Bi, Xiaobao, Yin, Juan, Chen, Ashley Guanbang, Liu, Chuan-Fa
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/139342
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author Bi, Xiaobao
Yin, Juan
Chen, Ashley Guanbang
Liu, Chuan-Fa
author2 School of Biological Sciences
author_facet School of Biological Sciences
Bi, Xiaobao
Yin, Juan
Chen, Ashley Guanbang
Liu, Chuan-Fa
author_sort Bi, Xiaobao
collection NTU
description The cell surface serves important functions such as the regulation of cell-cell and cell-environment interactions. The understanding and manipulation of the cell surface is important for a wide range of fundamental studies of cellular behavior and for biotechnological and medical applications. With the rapid advance of biology, chemistry and materials science, many strategies have been developed for the functionalization of bacterial and mammalian cell surfaces. Here, we review the recent development of chemical and enzymatic approaches to cell surface engineering with particular emphasis on discussing the advantages and limitations of each of these strategies.
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spelling ntu-10356/1393422020-05-19T03:12:51Z Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering Bi, Xiaobao Yin, Juan Chen, Ashley Guanbang Liu, Chuan-Fa School of Biological Sciences Science::Biological sciences Cell Surface Engineering Cell Therapy The cell surface serves important functions such as the regulation of cell-cell and cell-environment interactions. The understanding and manipulation of the cell surface is important for a wide range of fundamental studies of cellular behavior and for biotechnological and medical applications. With the rapid advance of biology, chemistry and materials science, many strategies have been developed for the functionalization of bacterial and mammalian cell surfaces. Here, we review the recent development of chemical and enzymatic approaches to cell surface engineering with particular emphasis on discussing the advantages and limitations of each of these strategies. ASTAR (Agency for Sci., Tech. and Research, S’pore) MOE (Min. of Education, S’pore) 2020-05-19T03:12:51Z 2020-05-19T03:12:51Z 2018 Journal Article Bi, X., Yin, J., Chen, A. G., & Liu, C.-F. (2018). Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering. Chemistry - A European Journal, 24(32), 8042-8050. doi:10.1002/chem.201883263 0947-6539 https://hdl.handle.net/10356/139342 10.1002/chem.201705049 29341307 2-s2.0-85043606412 32 24 8042 8050 en Chemistry - A European Journal This is the accepted version of the following article: Bi, X., Yin, J., Chen, A. G., & Liu, C.-F. (2018). Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering. Chemistry - A European Journal, 24(32), 8042-8050, which has been published in final form at dx.doi.org/10.1002/chem.201705049. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [https://authorservices.wiley.com/authorresources/Journal-Authors/licensing/self-archiving.html]."
spellingShingle Science::Biological sciences
Cell Surface Engineering
Cell Therapy
Bi, Xiaobao
Yin, Juan
Chen, Ashley Guanbang
Liu, Chuan-Fa
Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
title Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
title_full Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
title_fullStr Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
title_full_unstemmed Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
title_short Chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
title_sort chemical and enzymatic strategies for bacterial and mammalian cell surface engineering
topic Science::Biological sciences
Cell Surface Engineering
Cell Therapy
url https://hdl.handle.net/10356/139342
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AT liuchuanfa chemicalandenzymaticstrategiesforbacterialandmammaliancellsurfaceengineering