Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)

Much research effort has been put in to study layered compounds with transition metal dichalcogenides (TMDs) being one of the most studied compounds. Due to their extraordinary properties such as excellent electrochemical properties, tuneable band gaps, and low shear resistance due to weak van der W...

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Main Authors: Chia, Hui Ling, Naziah Mohamad Latiff, Sofer, Zdenĕk, Pumera, Martin
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/139352
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author Chia, Hui Ling
Naziah Mohamad Latiff
Sofer, Zdenĕk
Pumera, Martin
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Chia, Hui Ling
Naziah Mohamad Latiff
Sofer, Zdenĕk
Pumera, Martin
author_sort Chia, Hui Ling
collection NTU
description Much research effort has been put in to study layered compounds with transition metal dichalcogenides (TMDs) being one of the most studied compounds. Due to their extraordinary properties such as excellent electrochemical properties, tuneable band gaps, and low shear resistance due to weak van der Waals interactions between layers, TMDs have been found to have wide applications such as electrocatalysts for hydrogen evolution reactions, supercapacitors, biosensors, field-effect transistors (FETs), photovoltaics, and lubricant additives. In very recent years, Group 5 transition metal ditellurides have received an immense amount of research attention. However to date, little has been known of the potential toxicities posed by these materials. As such, we conducted the cytotoxicity study by incubating various concentrations of the Group 5 transition metal ditellurides (MTe2 ; M=V, Nb, Ta) with human lung carcinoma epithelial A549 cells for 24 hours and the remaining cell viabilities after treatment was measured. Our findings indicate that VTe2 is highly toxic whereas NbTe2 and TaTe2 are deemed to exhibit mild toxicities. This study constitutes an exemplary first step towards the understanding of the Group 5 transition metal ditellurides' toxicity effects in preparation for their possible future commercialisation.
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spelling ntu-10356/1393522020-05-19T04:12:32Z Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta) Chia, Hui Ling Naziah Mohamad Latiff Sofer, Zdenĕk Pumera, Martin School of Physical and Mathematical Sciences Interdisciplinary Graduate School (IGS) NTU Institute for Health Technologies Science::Chemistry Cytotoxicity Ditellurides Much research effort has been put in to study layered compounds with transition metal dichalcogenides (TMDs) being one of the most studied compounds. Due to their extraordinary properties such as excellent electrochemical properties, tuneable band gaps, and low shear resistance due to weak van der Waals interactions between layers, TMDs have been found to have wide applications such as electrocatalysts for hydrogen evolution reactions, supercapacitors, biosensors, field-effect transistors (FETs), photovoltaics, and lubricant additives. In very recent years, Group 5 transition metal ditellurides have received an immense amount of research attention. However to date, little has been known of the potential toxicities posed by these materials. As such, we conducted the cytotoxicity study by incubating various concentrations of the Group 5 transition metal ditellurides (MTe2 ; M=V, Nb, Ta) with human lung carcinoma epithelial A549 cells for 24 hours and the remaining cell viabilities after treatment was measured. Our findings indicate that VTe2 is highly toxic whereas NbTe2 and TaTe2 are deemed to exhibit mild toxicities. This study constitutes an exemplary first step towards the understanding of the Group 5 transition metal ditellurides' toxicity effects in preparation for their possible future commercialisation. MOE (Min. of Education, S’pore) 2020-05-19T04:12:32Z 2020-05-19T04:12:32Z 2017 Journal Article Chia, H. L., Naziah Mohamad Latiff, Sofer, Z., & Pumera, M. (2018). Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, NB, Ta). Chemistry - A European Journal, 24(1), 206-211. doi:10.1002/chem.201704316 0947-6539 https://hdl.handle.net/10356/139352 10.1002/chem.201704316 29027716 2-s2.0-85035205390 1 24 206 211 en Chemistry - A European Journal This is the accepted version of the following article: Chia, H. L., Naziah Mohamad Latiff, Sofer, Z., & Pumera, M. (2018). Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, NB, Ta). Chemistry - A European Journal, 24(1), 206-211, which has been published in final form at dx.doi.org/10.1002/chem.201704316. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [https://authorservices.wiley.com/authorresources/Journal-Authors/licensing/self-archiving.html]."
spellingShingle Science::Chemistry
Cytotoxicity
Ditellurides
Chia, Hui Ling
Naziah Mohamad Latiff
Sofer, Zdenĕk
Pumera, Martin
Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)
title Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)
title_full Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)
title_fullStr Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)
title_full_unstemmed Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)
title_short Cytotoxicity of group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta)
title_sort cytotoxicity of group 5 transition metal ditellurides mte2 m v nb ta
topic Science::Chemistry
Cytotoxicity
Ditellurides
url https://hdl.handle.net/10356/139352
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