Adaptor protein WDFY3 is neuroprotective by counteracting age-dependent decline in proteostasis

Age-dependent decline in proteostasis increases vulnerability of neuronal cells to oxidative stress, altered energy homeostasis and protein aggregation. Recent studies have suggested an adaptor role for BEACH-domain containing proteins (BDCPs) in autophagy-mediated clearance of protein aggregates in...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Fun, Xiu Hui
Άλλοι συγγραφείς: Guillaume Thibault
Μορφή: Thesis-Doctor of Philosophy
Γλώσσα:English
Έκδοση: Nanyang Technological University 2020
Θέματα:
Διαθέσιμο Online:https://hdl.handle.net/10356/139649