Adaptor protein WDFY3 is neuroprotective by counteracting age-dependent decline in proteostasis

Age-dependent decline in proteostasis increases vulnerability of neuronal cells to oxidative stress, altered energy homeostasis and protein aggregation. Recent studies have suggested an adaptor role for BEACH-domain containing proteins (BDCPs) in autophagy-mediated clearance of protein aggregates in...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Fun, Xiu Hui
Rannpháirtithe: Guillaume Thibault
Formáid: Thesis-Doctor of Philosophy
Teanga:English
Foilsithe / Cruthaithe: Nanyang Technological University 2020
Ábhair:
Rochtain ar líne:https://hdl.handle.net/10356/139649