Adaptor protein WDFY3 is neuroprotective by counteracting age-dependent decline in proteostasis
Age-dependent decline in proteostasis increases vulnerability of neuronal cells to oxidative stress, altered energy homeostasis and protein aggregation. Recent studies have suggested an adaptor role for BEACH-domain containing proteins (BDCPs) in autophagy-mediated clearance of protein aggregates in...
Príomhchruthaitheoir: | |
---|---|
Rannpháirtithe: | |
Formáid: | Thesis-Doctor of Philosophy |
Teanga: | English |
Foilsithe / Cruthaithe: |
Nanyang Technological University
2020
|
Ábhair: | |
Rochtain ar líne: | https://hdl.handle.net/10356/139649 |