Adaptor protein WDFY3 is neuroprotective by counteracting age-dependent decline in proteostasis

Age-dependent decline in proteostasis increases vulnerability of neuronal cells to oxidative stress, altered energy homeostasis and protein aggregation. Recent studies have suggested an adaptor role for BEACH-domain containing proteins (BDCPs) in autophagy-mediated clearance of protein aggregates in...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter: Fun, Xiu Hui
Andre forfattere: Guillaume Thibault
Format: Thesis-Doctor of Philosophy
Sprog:English
Udgivet: Nanyang Technological University 2020
Fag:
Online adgang:https://hdl.handle.net/10356/139649