Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation
Purpose: To compare the postoperative higher-order-aberrations (HOAs) after hyperopic small incision lenticule extraction (SMILE), hyperopic laser-assisted in situ keratomileusis (LASIK), and lenticule implantation for correction of hyperopia. Methods: Eighteen monkeys were divided to six groups: +2...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2020
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| Online Access: | https://hdl.handle.net/10356/140226 |
| _version_ | 1826121954477735936 |
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| author | Liu, Yu-Chi Wen, Jiaxin Teo, Ericia Pei Wen Williams, Geraint P. Lwin, Nyein Chan Mehta, Jodhbir Singh |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Liu, Yu-Chi Wen, Jiaxin Teo, Ericia Pei Wen Williams, Geraint P. Lwin, Nyein Chan Mehta, Jodhbir Singh |
| author_sort | Liu, Yu-Chi |
| collection | NTU |
| description | Purpose: To compare the postoperative higher-order-aberrations (HOAs) after hyperopic small incision lenticule extraction (SMILE), hyperopic laser-assisted in situ keratomileusis (LASIK), and lenticule implantation for correction of hyperopia. Methods: Eighteen monkeys were divided to six groups: +2.00 D and +4.00 D hyperopic SMILE, +2.00 D and +4.00 D hyperopic LASIK (n = 6 eyes for each), and lenticule implantation with a −2.00 D and −4.00 D lenticule (n = 3 eyes for each). The corneal HOAs were evaluated preoperatively and 3-month postoperatively. Results: At 3-month postoperatively, the spherical aberrations significantly increased toward negative direction in all +4.00 D groups (all P < 0.05). There was a significant change toward more negative values in the third-order vertical coma in the SMILE +4.00 D and LASIK +4.00 D groups (P = 0.026 and P = 0.036, respectively). There were also significant changes in the third-order horizontal trefoil (P = 0.034) and oblique secondary astigmatism (P = 0.012) in the LASIK +4.00 D group. In the eyes that underwent +4.00 D lenticule implantation, the fourth-order horizontal quatrefoil significantly increased (P = 0.029). In low hyperopia correction (+2.00 D), treatment with lenticule implantation tended to have less changes in HOAs, compared to the other two groups. Conclusions: In hyperopic SMILE, hyperopic LASIK or lenticule implantation surgery, significant induction of third- and fourth-order HOAs were seen in moderate hyperopia correction but not in low hyperopia correction. In low hyperopia treatment, lenticule implantation might offer a favorable trend in the aspect of HOAs. Translational Relevance: The results provided the knowledge of surgically induced HOAs and understanding of the effects of surgery in different types of hyperopic correction. |
| first_indexed | 2024-10-01T05:40:55Z |
| format | Journal Article |
| id | ntu-10356/140226 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:40:55Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1402262023-07-14T15:58:37Z Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation Liu, Yu-Chi Wen, Jiaxin Teo, Ericia Pei Wen Williams, Geraint P. Lwin, Nyein Chan Mehta, Jodhbir Singh School of Materials Science & Engineering Engineering::Materials Higher-order Aberrations Hyperopia Purpose: To compare the postoperative higher-order-aberrations (HOAs) after hyperopic small incision lenticule extraction (SMILE), hyperopic laser-assisted in situ keratomileusis (LASIK), and lenticule implantation for correction of hyperopia. Methods: Eighteen monkeys were divided to six groups: +2.00 D and +4.00 D hyperopic SMILE, +2.00 D and +4.00 D hyperopic LASIK (n = 6 eyes for each), and lenticule implantation with a −2.00 D and −4.00 D lenticule (n = 3 eyes for each). The corneal HOAs were evaluated preoperatively and 3-month postoperatively. Results: At 3-month postoperatively, the spherical aberrations significantly increased toward negative direction in all +4.00 D groups (all P < 0.05). There was a significant change toward more negative values in the third-order vertical coma in the SMILE +4.00 D and LASIK +4.00 D groups (P = 0.026 and P = 0.036, respectively). There were also significant changes in the third-order horizontal trefoil (P = 0.034) and oblique secondary astigmatism (P = 0.012) in the LASIK +4.00 D group. In the eyes that underwent +4.00 D lenticule implantation, the fourth-order horizontal quatrefoil significantly increased (P = 0.029). In low hyperopia correction (+2.00 D), treatment with lenticule implantation tended to have less changes in HOAs, compared to the other two groups. Conclusions: In hyperopic SMILE, hyperopic LASIK or lenticule implantation surgery, significant induction of third- and fourth-order HOAs were seen in moderate hyperopia correction but not in low hyperopia correction. In low hyperopia treatment, lenticule implantation might offer a favorable trend in the aspect of HOAs. Translational Relevance: The results provided the knowledge of surgically induced HOAs and understanding of the effects of surgery in different types of hyperopic correction. NRF (Natl Research Foundation, S’pore) NMRC (Natl Medical Research Council, S’pore) MOH (Min. of Health, S’pore) Published version 2020-05-27T07:45:01Z 2020-05-27T07:45:01Z 2018 Journal Article Liu, Y.-C., Wen, J., Teo, E. P. W., Williams, G. P., Lwin, N. C., & Mehta, J. S. (2018). Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation. Translational Vision Science & Technology, 7(2), 15-. doi:10.1167/tvst.7.2.15 2164-2591 https://hdl.handle.net/10356/140226 10.1167/tvst.7.2.15 29616154 2-s2.0-85045011021 2 7 en Translational Vision Science & Technology © 2018 The Authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. application/pdf |
| spellingShingle | Engineering::Materials Higher-order Aberrations Hyperopia Liu, Yu-Chi Wen, Jiaxin Teo, Ericia Pei Wen Williams, Geraint P. Lwin, Nyein Chan Mehta, Jodhbir Singh Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation |
| title | Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation |
| title_full | Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation |
| title_fullStr | Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation |
| title_full_unstemmed | Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation |
| title_short | Higher-order-aberrations following hyperopia treatment : small incision lenticule extraction, laser-assisted in situ keratomileusis and lenticule implantation |
| title_sort | higher order aberrations following hyperopia treatment small incision lenticule extraction laser assisted in situ keratomileusis and lenticule implantation |
| topic | Engineering::Materials Higher-order Aberrations Hyperopia |
| url | https://hdl.handle.net/10356/140226 |
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