Structural and biochemical studies of erythromycin-resistance methyltransferases : insights into structure-based drug design
Erm38 is a methyltransferase from Mycolicibacterium smegmatis that methylates the A2058 position in 23S rRNA using S-adenosyl methionine (SAM) as methyl donor. It confers resistance to macrolides, lincosamides and streptogramins in Gram-positive bacteria and mycobacteria. In this project, we obtaine...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Final Year Project (FYP) |
| Language: | English |
| Published: |
Nanyang Technological University
2020
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/140816 |