Matrix-assisted laser desorption ionization mass spectrometry imaging of key proteins in corneal samples from lattice dystrophy patients with TGFBI-H626R and TGFBI-R124C mutations

Matrix-assisted laser desorption ionization mass spectrometry imaging of key proteins in corneal samples from lattice dystrophy patients with TGFBI-H626R and TGFBI-R124C mutations

Scope: The purpose of this study is to identify and visualize the spatial distribution of proteins present in amyloid corneal deposits of TGFBI‐CD patients using Mass Spectrometry Imaging (MSI) and compare it with healthy control cornea. Corneal Dystrophies (CD) constitute a group of genetically inh...

Full description

Bibliographic Details
Main Authors: Venkatraman, Anandalakshmi, Hochart, Guillaume, Bonnel, David, Stauber, Jonathan, Shimmura, Shigeto, Rajamani, Lakshminaryanan, Pervushin, Konstantin, Mehta, Jodhbir S.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Corneal Dystrophy
Matrix-assisted Laser Desorption/Ionization
Online Access:https://hdl.handle.net/10356/141816

Similar Items

Similar Items