Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

The ability of DENV2 to display different morphologies (hence different antigenic properties) complicates vaccine and therapeutics development. Previous studies showed most strains of laboratory adapted DENV2 particles changed from smooth to "bumpy" surfaced morphology when the temperature...

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Bibliographic Details
Main Authors: Lim, Xin-Ni, Shan, Chao, Marzinek, Jan K., Dong, Hongping, Ng, Thiam Seng, Ooi, Justin Seng Geap, Fibriansah, Guntur, Wang, Jiaqi, Verma, Chandra Shekhar, Bond, Peter John, Shi, Pei-Yong, Lok, Shee-mei
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Dengue Virus
DENV2
Online Access:https://hdl.handle.net/10356/142196

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