Methanogens in humans : potentially beneficial or harmful for health
Methanogens are anaerobic prokaryotes from the domain archaea that utilize hydrogen to reduce carbon dioxide, acetate, and a variety of methyl compounds into methane. Earlier believed to inhabit only the extreme environments, these organisms are now reported to be found in various environments inclu...
| Main Authors: | , , |
|---|---|
| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/142204 |
| _version_ | 1811678112322158592 |
|---|---|
| author | Chaudhary, Prem Prashant Conway, Patricia Lynne Schlundt, Jørgen |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Chaudhary, Prem Prashant Conway, Patricia Lynne Schlundt, Jørgen |
| author_sort | Chaudhary, Prem Prashant |
| collection | NTU |
| description | Methanogens are anaerobic prokaryotes from the domain archaea that utilize hydrogen to reduce carbon dioxide, acetate, and a variety of methyl compounds into methane. Earlier believed to inhabit only the extreme environments, these organisms are now reported to be found in various environments including mesophilic habitats and the human body. The biological significance of methanogens for humans has been re-evaluated in the last few decades. Their contribution towards pathogenicity has received much less attention than their bacterial counterparts. In humans, methanogens have been studied in the gastrointestinal tract, mouth, and vagina, and considerable focus has shifted towards elucidating their possible role in the progression of disease conditions in humans. Methanoarchaea are also part of the human skin microbiome and proposed to play a role in ammonia turnover. Compared to hundreds of different bacterial species, the human body harbors only a handful of methanogen species represented by Methanobrevibacter smithii, Methanobrevibacter oralis, Methanosphaera stadtmanae, Methanomassiliicoccus luminyensis, Candidatus Methanomassiliicoccus intestinalis, and Candidatus Methanomethylophilus alvus. Their presence in the human gut suggests an indirect correlation with severe diseases of the colon. In this review, we examine the current knowledge about the methanoarchaea in the human body and possible beneficial or less favorable interactions. |
| first_indexed | 2024-10-01T02:48:05Z |
| format | Journal Article |
| id | ntu-10356/142204 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:48:05Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1422042020-06-17T05:52:13Z Methanogens in humans : potentially beneficial or harmful for health Chaudhary, Prem Prashant Conway, Patricia Lynne Schlundt, Jørgen School of Mechanical and Aerospace Engineering Nanyang Technological University Food Technology Centre Engineering::Chemical engineering Archaea Methanogens Methanogens are anaerobic prokaryotes from the domain archaea that utilize hydrogen to reduce carbon dioxide, acetate, and a variety of methyl compounds into methane. Earlier believed to inhabit only the extreme environments, these organisms are now reported to be found in various environments including mesophilic habitats and the human body. The biological significance of methanogens for humans has been re-evaluated in the last few decades. Their contribution towards pathogenicity has received much less attention than their bacterial counterparts. In humans, methanogens have been studied in the gastrointestinal tract, mouth, and vagina, and considerable focus has shifted towards elucidating their possible role in the progression of disease conditions in humans. Methanoarchaea are also part of the human skin microbiome and proposed to play a role in ammonia turnover. Compared to hundreds of different bacterial species, the human body harbors only a handful of methanogen species represented by Methanobrevibacter smithii, Methanobrevibacter oralis, Methanosphaera stadtmanae, Methanomassiliicoccus luminyensis, Candidatus Methanomassiliicoccus intestinalis, and Candidatus Methanomethylophilus alvus. Their presence in the human gut suggests an indirect correlation with severe diseases of the colon. In this review, we examine the current knowledge about the methanoarchaea in the human body and possible beneficial or less favorable interactions. 2020-06-17T05:52:13Z 2020-06-17T05:52:13Z 2018 Journal Article Chaudhary, P. P., Conway, P. L., & Schlundt, J. (2018). Methanogens in humans : potentially beneficial or harmful for health. Applied microbiology and biotechnology, 102(7), 3095–3104. doi:10.1007/s00253-018-8871-2 0175-7598 https://hdl.handle.net/10356/142204 10.1007/s00253-018-8871-2 29497795 2-s2.0-85043782915 7 102 3095 3104 en Applied microbiology and biotechnology © 2018 Springer-Verlag GmbH Germany, part of Springer Nature. All rights reserved. |
| spellingShingle | Engineering::Chemical engineering Archaea Methanogens Chaudhary, Prem Prashant Conway, Patricia Lynne Schlundt, Jørgen Methanogens in humans : potentially beneficial or harmful for health |
| title | Methanogens in humans : potentially beneficial or harmful for health |
| title_full | Methanogens in humans : potentially beneficial or harmful for health |
| title_fullStr | Methanogens in humans : potentially beneficial or harmful for health |
| title_full_unstemmed | Methanogens in humans : potentially beneficial or harmful for health |
| title_short | Methanogens in humans : potentially beneficial or harmful for health |
| title_sort | methanogens in humans potentially beneficial or harmful for health |
| topic | Engineering::Chemical engineering Archaea Methanogens |
| url | https://hdl.handle.net/10356/142204 |
| work_keys_str_mv | AT chaudharypremprashant methanogensinhumanspotentiallybeneficialorharmfulforhealth AT conwaypatricialynne methanogensinhumanspotentiallybeneficialorharmfulforhealth AT schlundtjørgen methanogensinhumanspotentiallybeneficialorharmfulforhealth |