Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer
The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle, metabolic diseases, chronic inflammatory disease, and cancer development. A better understanding of the mechanisms of TRIB pseudokinases could provide new insights for disease development and help pro...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/142222 |
| _version_ | 1826122645973762048 |
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| author | Cui, Bing Eyers, Patrick A. Dobens, Leonard L. Tan, Nguan Soon Mace, Peter D. Link, Wolfgang A. Kiss-Toth, Endre Keeshan, Karen Nakamura, Takuro Pear, Warren S. Feseha, Yodit Johnston, Jessica Carracedo, Arkatiz Scheideler, Marcel llyas, Zabran Bauer, Robert C. Erusalimsky, Jorge D. Grzesik, Dominika Salamanca-Viloria, Juan Lv, Xiaoxi Jin, Yishi Li, Ke Velasco, Guillermo Shang, Shuang Lizcano, Jose M. Zhang, Xiaowei Zhou, Jichao Yu, Jiaojiao Hua, Fang Wang, Feng Liu, Shanshan Yu, Jinmei Hu, Zhuowei |
| author2 | School of Biological Sciences |
| author_facet | School of Biological Sciences Cui, Bing Eyers, Patrick A. Dobens, Leonard L. Tan, Nguan Soon Mace, Peter D. Link, Wolfgang A. Kiss-Toth, Endre Keeshan, Karen Nakamura, Takuro Pear, Warren S. Feseha, Yodit Johnston, Jessica Carracedo, Arkatiz Scheideler, Marcel llyas, Zabran Bauer, Robert C. Erusalimsky, Jorge D. Grzesik, Dominika Salamanca-Viloria, Juan Lv, Xiaoxi Jin, Yishi Li, Ke Velasco, Guillermo Shang, Shuang Lizcano, Jose M. Zhang, Xiaowei Zhou, Jichao Yu, Jiaojiao Hua, Fang Wang, Feng Liu, Shanshan Yu, Jinmei Hu, Zhuowei |
| author_sort | Cui, Bing |
| collection | NTU |
| description | The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle, metabolic diseases, chronic inflammatory disease, and cancer development. A better understanding of the mechanisms of TRIB pseudokinases could provide new insights for disease development and help promote TRIB proteins as novel therapeutic targets for drug discovery. At the 2nd International Symposium on Tribbles and Diseases held on May 7–9, 2018 in Beijing, China, a group of leading Tribbles scientists reported their findings and ongoing studies about the effects of the different TRIB proteins in the areas of immunity, metabolism, fundamental cell biology and cancer. Here, we summarize important and insightful overviews from 4 keynote lectures, 13 plenary lectures and 8 short talks that took place during this meeting. These findings may offer new insights for the understanding of the roles of TRIB pseudokinases in the development of various diseases. |
| first_indexed | 2024-10-01T05:51:33Z |
| format | Journal Article |
| id | ntu-10356/142222 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:51:33Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1422222023-02-28T16:57:44Z Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer Cui, Bing Eyers, Patrick A. Dobens, Leonard L. Tan, Nguan Soon Mace, Peter D. Link, Wolfgang A. Kiss-Toth, Endre Keeshan, Karen Nakamura, Takuro Pear, Warren S. Feseha, Yodit Johnston, Jessica Carracedo, Arkatiz Scheideler, Marcel llyas, Zabran Bauer, Robert C. Erusalimsky, Jorge D. Grzesik, Dominika Salamanca-Viloria, Juan Lv, Xiaoxi Jin, Yishi Li, Ke Velasco, Guillermo Shang, Shuang Lizcano, Jose M. Zhang, Xiaowei Zhou, Jichao Yu, Jiaojiao Hua, Fang Wang, Feng Liu, Shanshan Yu, Jinmei Hu, Zhuowei School of Biological Sciences Lee Kong Chian School of Medicine (LKCMedicine) Institute of Molecular and Cell Biology, A*STAR Science::Biological sciences Tribbles Immunology The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle, metabolic diseases, chronic inflammatory disease, and cancer development. A better understanding of the mechanisms of TRIB pseudokinases could provide new insights for disease development and help promote TRIB proteins as novel therapeutic targets for drug discovery. At the 2nd International Symposium on Tribbles and Diseases held on May 7–9, 2018 in Beijing, China, a group of leading Tribbles scientists reported their findings and ongoing studies about the effects of the different TRIB proteins in the areas of immunity, metabolism, fundamental cell biology and cancer. Here, we summarize important and insightful overviews from 4 keynote lectures, 13 plenary lectures and 8 short talks that took place during this meeting. These findings may offer new insights for the understanding of the roles of TRIB pseudokinases in the development of various diseases. MOE (Min. of Education, S’pore) Published version 2020-06-17T07:45:32Z 2020-06-17T07:45:32Z 2018 Journal Article Cui, B., Eyers, P. A., Dobens, L. L., Tan, N. S., Mace, P. D., Link, W. A., . . . Hu, Z. (2019). Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer. Acta Pharmaceutica Sinica B, 9(2), 443-454. doi:10.1016/j.apsb.2018.12.007 2211-3835 https://hdl.handle.net/10356/142222 10.1016/j.apsb.2018.12.007 2 9 443 454 en Acta Pharmaceutica Sinica B © 2019 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf |
| spellingShingle | Science::Biological sciences Tribbles Immunology Cui, Bing Eyers, Patrick A. Dobens, Leonard L. Tan, Nguan Soon Mace, Peter D. Link, Wolfgang A. Kiss-Toth, Endre Keeshan, Karen Nakamura, Takuro Pear, Warren S. Feseha, Yodit Johnston, Jessica Carracedo, Arkatiz Scheideler, Marcel llyas, Zabran Bauer, Robert C. Erusalimsky, Jorge D. Grzesik, Dominika Salamanca-Viloria, Juan Lv, Xiaoxi Jin, Yishi Li, Ke Velasco, Guillermo Shang, Shuang Lizcano, Jose M. Zhang, Xiaowei Zhou, Jichao Yu, Jiaojiao Hua, Fang Wang, Feng Liu, Shanshan Yu, Jinmei Hu, Zhuowei Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer |
| title | Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer |
| title_full | Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer |
| title_fullStr | Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer |
| title_full_unstemmed | Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer |
| title_short | Highlights of the 2nd international symposium on tribbles and diseases : tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer |
| title_sort | highlights of the 2nd international symposium on tribbles and diseases tribbles tremble in therapeutics for immunity metabolism fundamental cell biology and cancer |
| topic | Science::Biological sciences Tribbles Immunology |
| url | https://hdl.handle.net/10356/142222 |
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