Optical coherence tomography angiography : a review of current and future clinical applications

Optical coherence tomography angiography is a non-invasive imaging technique that now allows for simultaneous in vivo imaging of the morphology as well as the vasculature in the eye. In this review, we provide an update on the existing clinical applications of optical coherence tomography angiograph...

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Main Authors: Ang, Marcus, Tan, Anna Cheng Sim, Cheung, Gemmy Chui Ming, Keane, Pearse Andrew, Dolz-Marco, Rosa, Sng, Chelvin Cheryl Agnes, Schmetterer, Leopold
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142745
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author Ang, Marcus
Tan, Anna Cheng Sim
Cheung, Gemmy Chui Ming
Keane, Pearse Andrew
Dolz-Marco, Rosa
Sng, Chelvin Cheryl Agnes
Schmetterer, Leopold
author2 School of Materials Science and Engineering
author_facet School of Materials Science and Engineering
Ang, Marcus
Tan, Anna Cheng Sim
Cheung, Gemmy Chui Ming
Keane, Pearse Andrew
Dolz-Marco, Rosa
Sng, Chelvin Cheryl Agnes
Schmetterer, Leopold
author_sort Ang, Marcus
collection NTU
description Optical coherence tomography angiography is a non-invasive imaging technique that now allows for simultaneous in vivo imaging of the morphology as well as the vasculature in the eye. In this review, we provide an update on the existing clinical applications of optical coherence tomography angiography technology from the anterior to posterior segment of the eye. We also discuss the limitations of optical coherence tomography angiography technology, as well as the caveats to the interpretation of images. As current optical coherence tomography angiography systems are optimized for the retina, most studies have focused on interpreting images from conditions such as age related macular degeneration and retinal vascular diseases. However, the interpretation of these optical coherence tomography angiography images should be taken in consideration with other multi-modal imaging to overcome the limitations of each technique. In addition, there are a growing variety of clinical applications for optical coherence tomography angiography imaging in optic nerve head evaluation for glaucoma and optic neuropathies. Further developments in anterior optical coherence tomography angiography have now allowed for evaluation of anterior segment pathology such as glaucoma, ocular surface diseases, corneal vascularisation, and abnormal iris vasculature. Future developments in software could allow for improved segmentation and image resolution with automated measurements and analysis.
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spelling ntu-10356/1427452020-06-30T00:36:41Z Optical coherence tomography angiography : a review of current and future clinical applications Ang, Marcus Tan, Anna Cheng Sim Cheung, Gemmy Chui Ming Keane, Pearse Andrew Dolz-Marco, Rosa Sng, Chelvin Cheryl Agnes Schmetterer, Leopold School of Materials Science and Engineering Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Optical Coherence Tomography Angiography Optical coherence tomography angiography is a non-invasive imaging technique that now allows for simultaneous in vivo imaging of the morphology as well as the vasculature in the eye. In this review, we provide an update on the existing clinical applications of optical coherence tomography angiography technology from the anterior to posterior segment of the eye. We also discuss the limitations of optical coherence tomography angiography technology, as well as the caveats to the interpretation of images. As current optical coherence tomography angiography systems are optimized for the retina, most studies have focused on interpreting images from conditions such as age related macular degeneration and retinal vascular diseases. However, the interpretation of these optical coherence tomography angiography images should be taken in consideration with other multi-modal imaging to overcome the limitations of each technique. In addition, there are a growing variety of clinical applications for optical coherence tomography angiography imaging in optic nerve head evaluation for glaucoma and optic neuropathies. Further developments in anterior optical coherence tomography angiography have now allowed for evaluation of anterior segment pathology such as glaucoma, ocular surface diseases, corneal vascularisation, and abnormal iris vasculature. Future developments in software could allow for improved segmentation and image resolution with automated measurements and analysis. 2020-06-30T00:36:41Z 2020-06-30T00:36:41Z 2018 Journal Article Ang, M., Tan, A. C. S., Cheung, G. C. M., Keane, P. A., Dolz-Marco, R., Sng, C. C. A., & Schmetterer, L. (2018). Optical coherence tomography angiography : a review of current and future clinical applications. Graefe's Archive for Clinical and Experimental Ophthalmology, 256(2), 237-245. doi:10.1007/s00417-017-3896-2 0721-832X https://hdl.handle.net/10356/142745 10.1007/s00417-017-3896-2 29318383 2-s2.0-85040220646 2 256 237 245 en Graefe's Archive for Clinical and Experimental Ophthalmology © 2018 Springer-Verlag GmbH Germany, part of Springer Nature. All rights reserved.
spellingShingle Science::Medicine
Optical Coherence Tomography
Angiography
Ang, Marcus
Tan, Anna Cheng Sim
Cheung, Gemmy Chui Ming
Keane, Pearse Andrew
Dolz-Marco, Rosa
Sng, Chelvin Cheryl Agnes
Schmetterer, Leopold
Optical coherence tomography angiography : a review of current and future clinical applications
title Optical coherence tomography angiography : a review of current and future clinical applications
title_full Optical coherence tomography angiography : a review of current and future clinical applications
title_fullStr Optical coherence tomography angiography : a review of current and future clinical applications
title_full_unstemmed Optical coherence tomography angiography : a review of current and future clinical applications
title_short Optical coherence tomography angiography : a review of current and future clinical applications
title_sort optical coherence tomography angiography a review of current and future clinical applications
topic Science::Medicine
Optical Coherence Tomography
Angiography
url https://hdl.handle.net/10356/142745
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