Deciphering the Plasmodium epitranscriptome as a mechanism of translational control

Modifications to nucleosides present in ribonucleic acid (RNA) species have been shown to influence gene expression. Using a LC-MS/MS-based platform, we have characterized the full spectrum of modified ribonucleosides on the transfer RNA (tRNA) and messenger RNA (mRNA) in P. falciparum. We demonstra...

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Bibliographic Details
Main Author: Sinha, Ameya
Other Authors: Peter Preiser
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142964