Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples
Herein, we present an electrochemical sensing platform based on nanochannel-confined graphene quantum dots (GQDs) that is able to detect a spectrum of small analytes in complex samples with high sensitivity. Vertically ordered mesoporous silica-nanochannel film (VMSF) is decorated on the supporting...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/142995 |
| _version_ | 1811679252699938816 |
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| author | Lu, Lili Zhou, Lin Chen, Jie Yan, Fei Liu, Jiyang Dong, Xiaoping Xi, Fengna Chen, Peng |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Lu, Lili Zhou, Lin Chen, Jie Yan, Fei Liu, Jiyang Dong, Xiaoping Xi, Fengna Chen, Peng |
| author_sort | Lu, Lili |
| collection | NTU |
| description | Herein, we present an electrochemical sensing platform based on nanochannel-confined graphene quantum dots (GQDs) that is able to detect a spectrum of small analytes in complex samples with high sensitivity. Vertically ordered mesoporous silica-nanochannel film (VMSF) is decorated on the supporting electrode, conferring the electrode with excellent antifouling and anti-interference properties through steric exclusion and electrostatic repulsion. The synthesized GQDs with different functionalities are confined in the nanochannels of VMSF through electrophoresis, serving as the recognition element and signal amplifier. Without the usual need of tedious pretreatment, ultrasensitive and fast detection of Hg2+, Cu2+, and Cd2+ (with limits of detection (LOD) of 9.8 pM, 8.3 pM, and 4.3 nM, respectively) and dopamine (LOD of 120 nM) in complex food (Hg2+-contaminated seafood), environmental (soil-leaching solution), and biological (serum) samples are realized as proof-of-concept demonstrations. |
| first_indexed | 2024-10-01T03:06:12Z |
| format | Journal Article |
| id | ntu-10356/142995 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:06:12Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1429952023-12-29T06:46:10Z Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples Lu, Lili Zhou, Lin Chen, Jie Yan, Fei Liu, Jiyang Dong, Xiaoping Xi, Fengna Chen, Peng School of Chemical and Biomedical Engineering Engineering::Chemical engineering Graphene Quantum Dots Vertically Ordered Mesoporous Silica-nanochannel Herein, we present an electrochemical sensing platform based on nanochannel-confined graphene quantum dots (GQDs) that is able to detect a spectrum of small analytes in complex samples with high sensitivity. Vertically ordered mesoporous silica-nanochannel film (VMSF) is decorated on the supporting electrode, conferring the electrode with excellent antifouling and anti-interference properties through steric exclusion and electrostatic repulsion. The synthesized GQDs with different functionalities are confined in the nanochannels of VMSF through electrophoresis, serving as the recognition element and signal amplifier. Without the usual need of tedious pretreatment, ultrasensitive and fast detection of Hg2+, Cu2+, and Cd2+ (with limits of detection (LOD) of 9.8 pM, 8.3 pM, and 4.3 nM, respectively) and dopamine (LOD of 120 nM) in complex food (Hg2+-contaminated seafood), environmental (soil-leaching solution), and biological (serum) samples are realized as proof-of-concept demonstrations. MOE (Min. of Education, S’pore) Accepted version 2020-07-20T04:51:02Z 2020-07-20T04:51:02Z 2018 Journal Article Lu, L., Zhou, L., Chen, J., Yan, F., Liu, J., Dong, X., . . . Chen, P. (2018). Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples. ACS Nano, 12(12), 12673-12681. doi:10.1021/acsnano.8b07564 1936-0851 https://hdl.handle.net/10356/142995 10.1021/acsnano.8b07564 30485066 2-s2.0-85059463430 12 12 12673 12681 en ACS Nano This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Nano, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acsnano.8b07564 application/pdf |
| spellingShingle | Engineering::Chemical engineering Graphene Quantum Dots Vertically Ordered Mesoporous Silica-nanochannel Lu, Lili Zhou, Lin Chen, Jie Yan, Fei Liu, Jiyang Dong, Xiaoping Xi, Fengna Chen, Peng Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| title | Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| title_full | Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| title_fullStr | Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| title_full_unstemmed | Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| title_short | Nanochannel-confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| title_sort | nanochannel confined graphene quantum dots for ultrasensitive electrochemical analysis of complex samples |
| topic | Engineering::Chemical engineering Graphene Quantum Dots Vertically Ordered Mesoporous Silica-nanochannel |
| url | https://hdl.handle.net/10356/142995 |
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