Delineation of critical amino acids in activation function 1 of progesterone receptor for recruitment of transcription coregulators
The activation functions AF1 and AF2 of nuclear receptors mediate the recruitment of coregulators in gene regulation. AF1 is mapped to the highly variable and intrinsically unstructured N terminal domain and AF2 lies in the conserved ligand binding domain. The unstructured nature of AF1 offers struc...
Main Authors: | Woo, Amanda Rui En, Sze, Siu Kwan, Chung, Hwa Hwa, Lin, Valerie Chun Ling |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/143287 |
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