Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex
An efficient bioinspired deamination method of both natural and unnatural amino acid derivatives has been developed. This method provides easy access to a wide variety of useful α, β‐unsaturated carbonyl compounds. The reaction is realized with two transition metal catalysts (palladium and Nickel) i...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/143699 |
| _version_ | 1811689696982466560 |
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| author | Deng, Gongtao Chen, Jie Sun, Wangbin Bian, Kehan Jiang, Yaojia Loh, Teck-Peng |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Deng, Gongtao Chen, Jie Sun, Wangbin Bian, Kehan Jiang, Yaojia Loh, Teck-Peng |
| author_sort | Deng, Gongtao |
| collection | NTU |
| description | An efficient bioinspired deamination method of both natural and unnatural amino acid derivatives has been developed. This method provides easy access to a wide variety of useful α, β‐unsaturated carbonyl compounds. The reaction is realized with two transition metal catalysts (palladium and Nickel) in‐easy handling procedure. A possible reaction pathway is also proposed and the control experiments support the involvement of the palladium‐catalyzed inert sp3 C−H activation as one of the key steps. |
| first_indexed | 2024-10-01T05:52:13Z |
| format | Journal Article |
| id | ntu-10356/143699 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:52:13Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1436992020-09-17T05:11:08Z Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex Deng, Gongtao Chen, Jie Sun, Wangbin Bian, Kehan Jiang, Yaojia Loh, Teck-Peng School of Physical and Mathematical Sciences Engineering::Chemical engineering::Biochemical engineering Bioinspired Reactions C-H Activation An efficient bioinspired deamination method of both natural and unnatural amino acid derivatives has been developed. This method provides easy access to a wide variety of useful α, β‐unsaturated carbonyl compounds. The reaction is realized with two transition metal catalysts (palladium and Nickel) in‐easy handling procedure. A possible reaction pathway is also proposed and the control experiments support the involvement of the palladium‐catalyzed inert sp3 C−H activation as one of the key steps. 2020-09-17T05:11:08Z 2020-09-17T05:11:08Z 2018 Journal Article Deng, G., Chen, J., Sun, W., Bian, K., Jiang, Y., & Loh, T.-P. (2018). Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex. Advanced Synthesis & Catalysis, 360(20), 3900-3905. doi:10.1002/adsc.201800823 1615-4169 https://hdl.handle.net/10356/143699 10.1002/adsc.201800823 20 360 3900 3905 en Advanced Synthesis & Catalysis © 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim. All rights reserved. |
| spellingShingle | Engineering::Chemical engineering::Biochemical engineering Bioinspired Reactions C-H Activation Deng, Gongtao Chen, Jie Sun, Wangbin Bian, Kehan Jiang, Yaojia Loh, Teck-Peng Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex |
| title | Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex |
| title_full | Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex |
| title_fullStr | Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex |
| title_full_unstemmed | Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex |
| title_short | Bioinspired deamination of α-amino acid derivatives catalyzed by a palladium/nickel complex |
| title_sort | bioinspired deamination of α amino acid derivatives catalyzed by a palladium nickel complex |
| topic | Engineering::Chemical engineering::Biochemical engineering Bioinspired Reactions C-H Activation |
| url | https://hdl.handle.net/10356/143699 |
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