The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting
Background: Weight loss (WL) quality is as important as quantity. Maximizing muscle retention during WL is key and leucine (Leu) has been identified as a key contributor. Further, food cravings, appetite sensations and mood are associated with WL diet success. However, the effects of Leu dose on the...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/144473 |
| _version_ | 1826123096339251200 |
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| author | Lee, Yi Shin |
| author2 | - |
| author_facet | - Lee, Yi Shin |
| author_sort | Lee, Yi Shin |
| collection | NTU |
| description | Background: Weight loss (WL) quality is as important as quantity. Maximizing muscle retention during WL is key and leucine (Leu) has been identified as a key contributor. Further, food cravings, appetite sensations and mood are associated with WL diet success. However, the effects of Leu dose on these variables are not clear. Purpose: To investigate if there is a dose-response relationship of Leu on changes in body mass, appetite markers, food cravings and mood, after a 4-week alternate day fasting (ADF) intervention in Asian males with body mass index (BMI) ≥ 23 kg/m2. Methods: A parallel, four-arm, double-blinded, randomized controlled trial design was utilized, where 22 participants were allocated into 4 groups receiving 0.02-0.08 g/kg BW/d of Leu. Participants went through 4 weeks of ADF, with a 25% daily caloric deficit. Changes in body mass were measured using a weighing scale, appetite markers with visual analogue scales, food cravings with the Food Craving Questionnaire-Trait-reduced and mood with the Brunel Mood Scale (BRUMS), pre- and post-intervention. Results: Only significant decreases in body mass, appetite markers and the BRUMS vigour subscale scores were observed after the 4-week ADF intervention (mean = -3.69 kg; -7.79 mm; 1.58 arbitrary units, respectively). However, there was no effect of increasing Leu dosage on these observed differences. No differences were observed in the other variables. Conclusions: There is no dose-response relationship of Leu on changes in body mass, appetite markers, food cravings and mood after a 4-week ADF intervention in Asian males with BMI ≥ 23 kg/m2. |
| first_indexed | 2024-10-01T05:59:03Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/144473 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:59:03Z |
| publishDate | 2020 |
| publisher | Nanyang Technological University |
| record_format | dspace |
| spelling | ntu-10356/1444732020-11-08T20:11:10Z The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting Lee, Yi Shin - Yang Yifan yifan.yang@nie.edu.sg Science::Biological sciences::Human anatomy and physiology Background: Weight loss (WL) quality is as important as quantity. Maximizing muscle retention during WL is key and leucine (Leu) has been identified as a key contributor. Further, food cravings, appetite sensations and mood are associated with WL diet success. However, the effects of Leu dose on these variables are not clear. Purpose: To investigate if there is a dose-response relationship of Leu on changes in body mass, appetite markers, food cravings and mood, after a 4-week alternate day fasting (ADF) intervention in Asian males with body mass index (BMI) ≥ 23 kg/m2. Methods: A parallel, four-arm, double-blinded, randomized controlled trial design was utilized, where 22 participants were allocated into 4 groups receiving 0.02-0.08 g/kg BW/d of Leu. Participants went through 4 weeks of ADF, with a 25% daily caloric deficit. Changes in body mass were measured using a weighing scale, appetite markers with visual analogue scales, food cravings with the Food Craving Questionnaire-Trait-reduced and mood with the Brunel Mood Scale (BRUMS), pre- and post-intervention. Results: Only significant decreases in body mass, appetite markers and the BRUMS vigour subscale scores were observed after the 4-week ADF intervention (mean = -3.69 kg; -7.79 mm; 1.58 arbitrary units, respectively). However, there was no effect of increasing Leu dosage on these observed differences. No differences were observed in the other variables. Conclusions: There is no dose-response relationship of Leu on changes in body mass, appetite markers, food cravings and mood after a 4-week ADF intervention in Asian males with BMI ≥ 23 kg/m2. Bachelor of Science (Sport Science and Management) 2020-11-06T05:29:18Z 2020-11-06T05:29:18Z 2020 Final Year Project (FYP) https://hdl.handle.net/10356/144473 en application/pdf Nanyang Technological University |
| spellingShingle | Science::Biological sciences::Human anatomy and physiology Lee, Yi Shin The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting |
| title | The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting |
| title_full | The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting |
| title_fullStr | The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting |
| title_full_unstemmed | The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting |
| title_short | The dose-response relationship of leucine on food cravings, appetite and mood in young men on intermittent fasting |
| title_sort | dose response relationship of leucine on food cravings appetite and mood in young men on intermittent fasting |
| topic | Science::Biological sciences::Human anatomy and physiology |
| url | https://hdl.handle.net/10356/144473 |
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