Hepatic PPARα is critical in the metabolic adaptation to sepsis

Hepatic PPARα is critical in the metabolic adaptation to sepsis

Although the role of inflammation to combat infection is known, the contribution of metabolic changes in response to sepsis is poorly understood. Sepsis induces the release of lipid mediators, many of which activate nuclear receptors such as the peroxisome proliferator-activated receptor (PPAR)α, wh...

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Bibliographic Details
Main Authors: Paumelle, Réjane, Haas, Joel T., Hennuyer, Nathalie, Baugé, Eric, Deleye, Yann, Mesotten, Dieter, Langouche, Lies, Vanhoutte, Jonathan, Cudejko, Céline, Wouters, Kristiaan, Hannou, Sarah Anissa, Legry, Vanessa, Lancel, Steve, Lalloyer, Fanny, Polizzi, Arnaud, Smati, Sarra, Gourdy, Pierre, Vallez, Emmanuelle, Bouchaert, Emmanuel, Derudas, Bruno, Dehondt, Hélène, Gheeraert, Céline, Fleury, Sébastien, Tailleux, Anne, Montagner, Alexandra, Wahli, Walter, Van Den Berghe, Greet, Guillou, Hervé, Dombrowicz, David, Staels, Bart
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Medicine
Nuclear Receptors
Sepsis
Online Access:https://hdl.handle.net/10356/144807

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