Variable computed tomography appearances of COVID-19
The coronavirus disease 2019 (COVID-19) is typically diagnosed by specific assays that detect viral nucleic acid from the upper respiratory tract; however, this may miss infections involving only the lower airways. Computed tomography (CT) has been described as a diagnostic modality in the COVID-19...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/145196 |
| _version_ | 1824455998625021952 |
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| author | Lim, Zhan Ye Khoo, Hau Wei Hui, Terrence Chi Hong Kok, Shawn Shi Xian Kwan, Kenneth Eng Ling Young, Barnaby Edward Tan, Cher Heng Kaw, Gregory Jon Leng |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Lim, Zhan Ye Khoo, Hau Wei Hui, Terrence Chi Hong Kok, Shawn Shi Xian Kwan, Kenneth Eng Ling Young, Barnaby Edward Tan, Cher Heng Kaw, Gregory Jon Leng |
| author_sort | Lim, Zhan Ye |
| collection | NTU |
| description | The coronavirus disease 2019 (COVID-19) is typically diagnosed by specific assays that detect viral nucleic acid from the upper respiratory tract; however, this may miss infections involving only the lower airways. Computed tomography (CT) has been described as a diagnostic modality in the COVID-19 diagnosis and treatment plan. We present a case series with virologically confirmed COVID-19 pneumonia. Variable CT features were observed: consolidation with ground-glass opacities, ground-glass opacities with subpleural reticular bands, and an anterior-posterior gradient of lung abnormalities resembling that of acute respiratory distress syndrome. Evolution of CT findings was observed in one patient, where there was interval resolution of bilateral lung consolidation with development of bronchiolectasis and subpleural fibrotic bands. While sensitive for detecting lung parenchymal abnormalities in COVID-19 pneumonia, the use of CT for initial diagnosis is discouraged and should be reserved for specific clinical indications. Interpretation of chest CT findings should be correlated with duration of symptoms to better determine the disease stage and aid in patient management. |
| first_indexed | 2025-02-19T03:47:07Z |
| format | Journal Article |
| id | ntu-10356/145196 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:47:07Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1451962023-03-05T16:47:27Z Variable computed tomography appearances of COVID-19 Lim, Zhan Ye Khoo, Hau Wei Hui, Terrence Chi Hong Kok, Shawn Shi Xian Kwan, Kenneth Eng Ling Young, Barnaby Edward Tan, Cher Heng Kaw, Gregory Jon Leng Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Computed Tomography Coronavirus Disease The coronavirus disease 2019 (COVID-19) is typically diagnosed by specific assays that detect viral nucleic acid from the upper respiratory tract; however, this may miss infections involving only the lower airways. Computed tomography (CT) has been described as a diagnostic modality in the COVID-19 diagnosis and treatment plan. We present a case series with virologically confirmed COVID-19 pneumonia. Variable CT features were observed: consolidation with ground-glass opacities, ground-glass opacities with subpleural reticular bands, and an anterior-posterior gradient of lung abnormalities resembling that of acute respiratory distress syndrome. Evolution of CT findings was observed in one patient, where there was interval resolution of bilateral lung consolidation with development of bronchiolectasis and subpleural fibrotic bands. While sensitive for detecting lung parenchymal abnormalities in COVID-19 pneumonia, the use of CT for initial diagnosis is discouraged and should be reserved for specific clinical indications. Interpretation of chest CT findings should be correlated with duration of symptoms to better determine the disease stage and aid in patient management. Published version 2020-12-15T02:54:30Z 2020-12-15T02:54:30Z 2020 Journal Article Lim, Z. Y., Khoo, H. W., Hui, T. C. H., Kok, S. S. X., Kwan, K. E. L., Young, B. E., . . . Kaw, G. J. L. (2020). Variable computed tomography appearances of COVID-19. Singapore Medical Journal, 61(7), 387-391. doi:10.11622/smedj.2020066 0037-5675 https://hdl.handle.net/10356/145196 10.11622/smedj.2020066 32312025 7 61 387 391 en Singapore Medical Journal © 2020 Singapore Medical Association. All rights reserved. This paper was published in Singapore Medical Journal and is made available with permission of Singapore Medical Association. application/pdf |
| spellingShingle | Science::Medicine Computed Tomography Coronavirus Disease Lim, Zhan Ye Khoo, Hau Wei Hui, Terrence Chi Hong Kok, Shawn Shi Xian Kwan, Kenneth Eng Ling Young, Barnaby Edward Tan, Cher Heng Kaw, Gregory Jon Leng Variable computed tomography appearances of COVID-19 |
| title | Variable computed tomography appearances of COVID-19 |
| title_full | Variable computed tomography appearances of COVID-19 |
| title_fullStr | Variable computed tomography appearances of COVID-19 |
| title_full_unstemmed | Variable computed tomography appearances of COVID-19 |
| title_short | Variable computed tomography appearances of COVID-19 |
| title_sort | variable computed tomography appearances of covid 19 |
| topic | Science::Medicine Computed Tomography Coronavirus Disease |
| url | https://hdl.handle.net/10356/145196 |
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