Whole-cell phenotypic screening of Medicines for Malaria Venture Pathogen Box identifies specific inhibitors of Plasmodium falciparum late-stage development and egress

Whole-cell phenotypic screening of Medicines for Malaria Venture Pathogen Box identifies specific inhibitors of Plasmodium falciparum late-stage development and egress

We report a systematic, cellular phenotype-based antimalarial screening of the Medicines for Malaria Venture Pathogen Box collection, which facilitated the identification of specific blockers of late-stage intraerythrocytic development of Plasmodium falciparum First, from standard growth inhibition...

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Bibliographic Details
Main Authors: Patra, Alok Tanala, Hingamire, Tejashri, Belekar, Meenakshi A., Xiong, Aoli, Subramanian, Gowtham, Bozdech, Zbynek, Preiser, Peter, Shanmugam, Dhanasekaran, Chandramohanadas, Rajesh
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Phenotypic Screening
Plasmodium Falciparum
Online Access:https://hdl.handle.net/10356/145209

Internet

https://hdl.handle.net/10356/145209

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