3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants
Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implant...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Online Access: | https://hdl.handle.net/10356/145389 |
| _version_ | 1826118839102865408 |
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| author | Luis, Eric Pan, Matthew Houwen Bastola, Anil Kumar Bajpai, Ram Sing, Swee Leong Song, Juha Yeong, Wai Yee |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Luis, Eric Pan, Matthew Houwen Bastola, Anil Kumar Bajpai, Ram Sing, Swee Leong Song, Juha Yeong, Wai Yee |
| author_sort | Luis, Eric |
| collection | NTU |
| description | Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implantation. Similarly, 3D printed hydrogel scaffolds suffer from drawbacks of being mechanically weak and as a result patients are unable to execute immediate post-surgical weight-bearing ambulation and rehabilitation. To solve this problem, we have developed a 3D silicone meniscus implant which is (1) cytocompatible, (2) resistant to cyclic loading and mechanically similar to native meniscus, and (3) directly 3D printable. The main focus of this study is to determine whether the purity, composition, structure, dimensions and mechanical properties of silicone implants are affected by the use of a custom-made in-house 3D-printer. We have used the phosphate buffer saline (PBS) absorption test, Fourier transform infrared (FTIR) spectroscopy, surface profilometry, thermo-gravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM) to effectively assess and compare material properties between molded and 3D printed silicone samples. |
| first_indexed | 2024-10-01T04:50:05Z |
| format | Journal Article |
| id | ntu-10356/145389 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:50:05Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1453892020-12-26T20:11:28Z 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants Luis, Eric Pan, Matthew Houwen Bastola, Anil Kumar Bajpai, Ram Sing, Swee Leong Song, Juha Yeong, Wai Yee School of Chemical and Biomedical Engineering School of Mechanical and Aerospace Engineering Lee Kong Chian School of Medicine (LKCMedicine) Singapore Centre for 3D Printing Engineering Additive Manufacturing Meniscus Implants Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implantation. Similarly, 3D printed hydrogel scaffolds suffer from drawbacks of being mechanically weak and as a result patients are unable to execute immediate post-surgical weight-bearing ambulation and rehabilitation. To solve this problem, we have developed a 3D silicone meniscus implant which is (1) cytocompatible, (2) resistant to cyclic loading and mechanically similar to native meniscus, and (3) directly 3D printable. The main focus of this study is to determine whether the purity, composition, structure, dimensions and mechanical properties of silicone implants are affected by the use of a custom-made in-house 3D-printer. We have used the phosphate buffer saline (PBS) absorption test, Fourier transform infrared (FTIR) spectroscopy, surface profilometry, thermo-gravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM) to effectively assess and compare material properties between molded and 3D printed silicone samples. National Research Foundation (NRF) Published version This research is supported by the National Research Foundation, Prime Minister’s Office, Singapore under its Medium-Sized Center Funding scheme and the NTU Start-Up Grant. 2020-12-21T02:33:13Z 2020-12-21T02:33:13Z 2020 Journal Article Luis, E., Pan, M. H., Bastola, A. K., Bajpai, R., Sing, S. L., Song, J., & Yeong, W. Y. (2020). 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants. Polymers, 12(9), 2136-. doi:10.3390/polym12092136 2073-4360 https://hdl.handle.net/10356/145389 10.3390/polym12092136 32962059 9 12 2136 en Polymers © 2020 by the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). application/pdf |
| spellingShingle | Engineering Additive Manufacturing Meniscus Implants Luis, Eric Pan, Matthew Houwen Bastola, Anil Kumar Bajpai, Ram Sing, Swee Leong Song, Juha Yeong, Wai Yee 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants |
| title | 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants |
| title_full | 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants |
| title_fullStr | 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants |
| title_full_unstemmed | 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants |
| title_short | 3D printed silicone meniscus implants : influence of the 3D printing process on properties of silicone implants |
| title_sort | 3d printed silicone meniscus implants influence of the 3d printing process on properties of silicone implants |
| topic | Engineering Additive Manufacturing Meniscus Implants |
| url | https://hdl.handle.net/10356/145389 |
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