MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

Although photodynamic therapy (PDT) has been clinically applied tumor hypoxia still greatly restricts the performance of this oxygen-dependent oncological treatment. The delivery of oxygen donors to tumor may produce excessive reactive oxygen species (ROS) and damage the peripheral tissues. Herein,...

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Bibliographic Details
Main Authors: Zhao, Lingzhi, Li, Junyao, Su, Yaoquan, Yang, Liqiang, Chen, Liu, Qiang, Lei, Wang, Yajing, Xiang, Huijing, Tham, Phoebe Huijun, Peng, Juanjuan, Zhao, Yanli
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Medicine
Cell Death
Diseases
Online Access:https://hdl.handle.net/10356/145423

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