Interaction of nanoparticles with human skin
Nanoparticles (NPs) have been incorporated as active ingredients in a diverse range of consumer products such as oral hygiene products and cosmetics, increasing the possible interaction between NPs and the human body. Due to their UV filtering ability, titanium dioxide (TiO2) and zinc oxide (ZnO) NP...
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| Format: | Thesis-Master by Research |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/146115 |
| _version_ | 1826116165057904640 |
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| author | Goh, Bernice Huan Rong |
| author2 | Ng Kee Woei |
| author_facet | Ng Kee Woei Goh, Bernice Huan Rong |
| author_sort | Goh, Bernice Huan Rong |
| collection | NTU |
| description | Nanoparticles (NPs) have been incorporated as active ingredients in a diverse range of consumer products such as oral hygiene products and cosmetics, increasing the possible interaction between NPs and the human body. Due to their UV filtering ability, titanium dioxide (TiO2) and zinc oxide (ZnO) NPs have been widely utilized in sunscreens and whitening creams. The widespread usage of these NPs has led to increase concerns on the possible penetration of these NPs into skin and potential adverse outcomes to human skin due to prolong exposure to nano-enabled consumer skin products. In particular, the influence of NPs on wound healing has not been documented. In a wound scenario, application of nano-enabled skin products could lead to NPs interacting with the living skin cells and tissue. Thus, this study aims to evaluate the interaction of TiO2 and ZnO NPs with human epidermal keratinocytes, specifically in a wound setting and the biological outcomes resulted from this interaction. |
| first_indexed | 2024-10-01T04:06:53Z |
| format | Thesis-Master by Research |
| id | ntu-10356/146115 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:06:53Z |
| publishDate | 2021 |
| publisher | Nanyang Technological University |
| record_format | dspace |
| spelling | ntu-10356/1461152023-03-04T16:43:19Z Interaction of nanoparticles with human skin Goh, Bernice Huan Rong Ng Kee Woei School of Materials Science and Engineering KWNG@ntu.edu.sg Engineering::Materials Nanoparticles (NPs) have been incorporated as active ingredients in a diverse range of consumer products such as oral hygiene products and cosmetics, increasing the possible interaction between NPs and the human body. Due to their UV filtering ability, titanium dioxide (TiO2) and zinc oxide (ZnO) NPs have been widely utilized in sunscreens and whitening creams. The widespread usage of these NPs has led to increase concerns on the possible penetration of these NPs into skin and potential adverse outcomes to human skin due to prolong exposure to nano-enabled consumer skin products. In particular, the influence of NPs on wound healing has not been documented. In a wound scenario, application of nano-enabled skin products could lead to NPs interacting with the living skin cells and tissue. Thus, this study aims to evaluate the interaction of TiO2 and ZnO NPs with human epidermal keratinocytes, specifically in a wound setting and the biological outcomes resulted from this interaction. Master of Engineering 2021-01-27T01:43:16Z 2021-01-27T01:43:16Z 2020 Thesis-Master by Research Goh, B. H. R. (2020). Interaction of nanoparticles with human skin. Master's thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/146115 10.32657/10356/146115 en This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). application/pdf Nanyang Technological University |
| spellingShingle | Engineering::Materials Goh, Bernice Huan Rong Interaction of nanoparticles with human skin |
| title | Interaction of nanoparticles with human skin |
| title_full | Interaction of nanoparticles with human skin |
| title_fullStr | Interaction of nanoparticles with human skin |
| title_full_unstemmed | Interaction of nanoparticles with human skin |
| title_short | Interaction of nanoparticles with human skin |
| title_sort | interaction of nanoparticles with human skin |
| topic | Engineering::Materials |
| url | https://hdl.handle.net/10356/146115 |
| work_keys_str_mv | AT gohbernicehuanrong interactionofnanoparticleswithhumanskin |