Lgr5 marks adult progenitor cells contributing to skeletal muscle regeneration and sarcoma formation
Regeneration of adult skeletal muscle is driven largely by resident satellite cells, a stem cell population increasingly considered to display a high degree of molecular heterogeneity. In this study, we find that Lgr5, a receptor for Rspo and a potent mediator of Wnt/β-catenin signaling, marks a sub...
Main Authors: | Leung, Carly, Katzrin Bte Ahmad Murad, Tan, Adelyn Liang Thing, Yada, Swathi, Sagiraju, Sowmya, Bode, Peter Karl, Barker, Nick |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2021
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/146148 |
Similar Items
-
A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis
by: Tan, Si Hui, et al.
Published: (2021) -
Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus
by: Kostic, Lana, et al.
Published: (2024) -
Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus
by: Lana Kostic, et al.
Published: (2024-08-01) -
MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells
by: Ruben Moreno, et al.
Published: (2022-08-01) -
LGR5+ Intestinal Stem Cells Display Sex-Dependent Radiosensitivity
by: Ryan C. Zitter, et al.
Published: (2023-12-01)