Plasticity of the 340-loop in influenza neuraminidase offers new insight for antiviral drug development

The recently discovered 340-cavity in influenza neuraminidase (NA) N6 and N7 subtypes has introduced new possibilities for rational structure-based drug design. However, the plasticity of the 340-loop (residues 342-347) and the role of the 340-loop in NA activity and substrate binding have not been...

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Main Authors: Han, Nanyu, Ng, Justin Tze Yang, Li, Yanpeng, Mu, Yuguang, Huang, Zunxi
其他作者: School of Biological Sciences
格式: Journal Article
语言:English
出版: 2021
主题:
在线阅读:https://hdl.handle.net/10356/146355