Plasticity of the 340-loop in influenza neuraminidase offers new insight for antiviral drug development

Plasticity of the 340-loop in influenza neuraminidase offers new insight for antiviral drug development

The recently discovered 340-cavity in influenza neuraminidase (NA) N6 and N7 subtypes has introduced new possibilities for rational structure-based drug design. However, the plasticity of the 340-loop (residues 342-347) and the role of the 340-loop in NA activity and substrate binding have not been...

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Bibliographic Details
Main Authors: Han, Nanyu, Ng, Justin Tze Yang, Li, Yanpeng, Mu, Yuguang, Huang, Zunxi
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
Influenza
Neuraminidase
Online Access:https://hdl.handle.net/10356/146355

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