Discovering putative protein targets of small molecules : a study of the p53 activator Nutlin
Small molecule drugs bind to a pocket in disease causing target proteins based on complementarity in shape and physicochemical properties. There is a likelihood that other proteins could have binding sites that are structurally similar to the target protein. Binding to these other proteins could alt...
Main Authors: | Nguyen, Minh N., Sen, Neeladri, Lin, Meiyin, Joseph, Thomas Leonard, Vaz, Candida, Tanavde, Vivek, Way, Luke, Hupp, Ted, Verma, Chandra Shekhar, Madhusudhan, M. S. |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/146761 |
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