Catalytic properties of human apurinic/apyrimidinic endonuclease 1 (APE1) and development of biosensors of APE1 in living cells

Catalytic properties of human apurinic/apyrimidinic endonuclease 1 (APE1) and development of biosensors of APE1 in living cells

Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential enzyme involved in the DNA base excision repair pathway and responsible for restoring mutagenic and cytotoxic abasic lesions throughout cell cycles. APE1 will cleave the 5’ end phosphodiester backbone right next to the generated apurinic/ap...

书目详细资料
主要作者:	Wang, Tianxiang
其他作者:	Li Tianhu
格式:	Thesis-Doctor of Philosophy
语言:	English
出版:	Nanyang Technological University 2021
主题:	Science::Chemistry::Biochemistry
在线阅读:	https://hdl.handle.net/10356/147410

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