Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis
Synthetically versatile anthranils as a bifunctional amino source have been employed for the first time to enable direct amination on unactivated C(sp3)-H bonds of thioamides under Cp*CoIII catalysis. The excellent site-selectivity on primary C(sp3)-H bonds is observed for a diverse array of thioami...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2021
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| Online Access: | https://hdl.handle.net/10356/147429 |
| _version_ | 1811686713849806848 |
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| author | Liu, Rui-Hua Shan, Qi-Chao Hu, Xu-Hong Loh, Teck-Peng |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Liu, Rui-Hua Shan, Qi-Chao Hu, Xu-Hong Loh, Teck-Peng |
| author_sort | Liu, Rui-Hua |
| collection | NTU |
| description | Synthetically versatile anthranils as a bifunctional amino source have been employed for the first time to enable direct amination on unactivated C(sp3)-H bonds of thioamides under Cp*CoIII catalysis. The excellent site-selectivity on primary C(sp3)-H bonds is observed for a diverse array of thioamides with high functional group tolerance. Further applicability of the products is also highlighted through a series of interesting synthetic elaborations. |
| first_indexed | 2024-10-01T05:04:48Z |
| format | Journal Article |
| id | ntu-10356/147429 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:04:48Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1474292021-04-01T01:10:38Z Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis Liu, Rui-Hua Shan, Qi-Chao Hu, Xu-Hong Loh, Teck-Peng School of Physical and Mathematical Sciences Science::Chemistry Intermolecular Amidation Benzyl Thioethers Synthetically versatile anthranils as a bifunctional amino source have been employed for the first time to enable direct amination on unactivated C(sp3)-H bonds of thioamides under Cp*CoIII catalysis. The excellent site-selectivity on primary C(sp3)-H bonds is observed for a diverse array of thioamides with high functional group tolerance. Further applicability of the products is also highlighted through a series of interesting synthetic elaborations. 2021-04-01T01:10:38Z 2021-04-01T01:10:38Z 2019 Journal Article Liu, R., Shan, Q., Hu, X. & Loh, T. (2019). Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis. Chemical Communications, 55(38), 5519-5522. https://dx.doi.org/10.1039/c9cc01715a 1359-7345 https://hdl.handle.net/10356/147429 10.1039/c9cc01715a 31020280 2-s2.0-85065540002 38 55 5519 5522 en Chemical Communications © 2019 The Royal Society of Chemistry. All rights reserved. |
| spellingShingle | Science::Chemistry Intermolecular Amidation Benzyl Thioethers Liu, Rui-Hua Shan, Qi-Chao Hu, Xu-Hong Loh, Teck-Peng Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis |
| title | Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis |
| title_full | Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis |
| title_fullStr | Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis |
| title_full_unstemmed | Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis |
| title_short | Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*Co III catalysis |
| title_sort | site selective c sp3 h amination of thioamide with anthranils under cp co iii catalysis |
| topic | Science::Chemistry Intermolecular Amidation Benzyl Thioethers |
| url | https://hdl.handle.net/10356/147429 |
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