Temperature effects on the phase behaviour of PSBMA polymer
Poly(sulfobetaine methacrylate) (PSBMA) polymers is a promising material in biomedical and drug development due to their high hydrophilicity, good anti-biofouling property, anti-polyelectrolyte, and biocompatibility. It is a class of zwitterionic polymer with sulfobetaine and amine function groups g...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/147748 |
| _version_ | 1826116262923599872 |
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| author | Lim, Kai Loon |
| author2 | Yu Jing |
| author_facet | Yu Jing Lim, Kai Loon |
| author_sort | Lim, Kai Loon |
| collection | NTU |
| description | Poly(sulfobetaine methacrylate) (PSBMA) polymers is a promising material in biomedical and drug development due to their high hydrophilicity, good anti-biofouling property, anti-polyelectrolyte, and biocompatibility. It is a class of zwitterionic polymer with sulfobetaine and amine function groups giving it strong hydrophilic properties. Due to this property, it is widely used as a copolymer by grafting PSBMA onto other materials. However, the phase behaviour of PSBMA is not well established. Thus, the project analyses PSBMA polymer to determine its phase behaviour and develop a phase diagram of PSBMA polymer. The polymer is analysed experimentally by turbidity method via UV-Vis spectrometry. The phase transition temperature is determined from the spectra and plotted against a range of polymer concentration to determine the phase diagram. Results from the phase diagram show that the PSBMA sample display a single-phase closed loop of a mixture of both Upper Critical Solution Temperature (UCST) and Lower Critical Solution Temperature (LCST) behaviour. Besides, the UCST and LCST showed a trend of decreasing transition temperature as polymer concentration increase. |
| first_indexed | 2024-10-01T04:08:28Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/147748 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:08:28Z |
| publishDate | 2021 |
| publisher | Nanyang Technological University |
| record_format | dspace |
| spelling | ntu-10356/1477482023-03-04T15:44:16Z Temperature effects on the phase behaviour of PSBMA polymer Lim, Kai Loon Yu Jing School of Materials Science and Engineering Ming Lun Li yujing@ntu.edu.sg Engineering::Chemical engineering::Polymers and polymer manufacture Engineering::Materials::Biomaterials Poly(sulfobetaine methacrylate) (PSBMA) polymers is a promising material in biomedical and drug development due to their high hydrophilicity, good anti-biofouling property, anti-polyelectrolyte, and biocompatibility. It is a class of zwitterionic polymer with sulfobetaine and amine function groups giving it strong hydrophilic properties. Due to this property, it is widely used as a copolymer by grafting PSBMA onto other materials. However, the phase behaviour of PSBMA is not well established. Thus, the project analyses PSBMA polymer to determine its phase behaviour and develop a phase diagram of PSBMA polymer. The polymer is analysed experimentally by turbidity method via UV-Vis spectrometry. The phase transition temperature is determined from the spectra and plotted against a range of polymer concentration to determine the phase diagram. Results from the phase diagram show that the PSBMA sample display a single-phase closed loop of a mixture of both Upper Critical Solution Temperature (UCST) and Lower Critical Solution Temperature (LCST) behaviour. Besides, the UCST and LCST showed a trend of decreasing transition temperature as polymer concentration increase. Bachelor of Engineering (Materials Engineering) 2021-04-13T05:57:15Z 2021-04-13T05:57:15Z 2021 Final Year Project (FYP) Lim, K. L. (2021). Temperature effects on the phase behaviour of PSBMA polymer. Final Year Project (FYP), Nanyang Technological University, Singapore. https://hdl.handle.net/10356/147748 https://hdl.handle.net/10356/147748 en MSE/20/073 application/pdf Nanyang Technological University |
| spellingShingle | Engineering::Chemical engineering::Polymers and polymer manufacture Engineering::Materials::Biomaterials Lim, Kai Loon Temperature effects on the phase behaviour of PSBMA polymer |
| title | Temperature effects on the phase behaviour of PSBMA polymer |
| title_full | Temperature effects on the phase behaviour of PSBMA polymer |
| title_fullStr | Temperature effects on the phase behaviour of PSBMA polymer |
| title_full_unstemmed | Temperature effects on the phase behaviour of PSBMA polymer |
| title_short | Temperature effects on the phase behaviour of PSBMA polymer |
| title_sort | temperature effects on the phase behaviour of psbma polymer |
| topic | Engineering::Chemical engineering::Polymers and polymer manufacture Engineering::Materials::Biomaterials |
| url | https://hdl.handle.net/10356/147748 |
| work_keys_str_mv | AT limkailoon temperatureeffectsonthephasebehaviourofpsbmapolymer |