Synthesising missing modalities for multimodal MRI segmentation

Multiple MRI images modalities are extensively utilised in medical imaging tasks such as tumour segmentation as they account for information variability and image diversity. However, in practice, it is frequent that some modalities are missing in patients' data sources, and there is data imbala...

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Main Author: Rajasekara Pandian Akshaya Muthu
Other Authors: Jagath C Rajapakse
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/148195
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author Rajasekara Pandian Akshaya Muthu
author2 Jagath C Rajapakse
author_facet Jagath C Rajapakse
Rajasekara Pandian Akshaya Muthu
author_sort Rajasekara Pandian Akshaya Muthu
collection NTU
description Multiple MRI images modalities are extensively utilised in medical imaging tasks such as tumour segmentation as they account for information variability and image diversity. However, in practice, it is frequent that some modalities are missing in patients' data sources, and there is data imbalance due to varying imaging protocols and image corruption. Rather than re-acquiring all patient modality images as a complete set, it is more feasible to use the patients' existing modalities to synthesise the missing modalities and use this improved data for tumour segmentation. Therefore, we propose a generative adversarial network (GAN) that carries out missing modality synthesis for data completion and tumour segmentation. Our experiments were carried out using the Brain Tumour Image Segmentation Benchmark 2019 (BraTS ’19) dataset and our experiments support that the synthesis of the missing modality benefitted the tumour segmentation results and produced better results compared to other experiments with missing modality. Because of an impending technical disclosure being written, some details about the proposed model has been omitted from this report.
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spelling ntu-10356/1481952021-07-23T05:30:21Z Synthesising missing modalities for multimodal MRI segmentation Rajasekara Pandian Akshaya Muthu Jagath C Rajapakse School of Computer Science and Engineering ASJagath@ntu.edu.sg Engineering::Computer science and engineering::Computing methodologies::Artificial intelligence Multiple MRI images modalities are extensively utilised in medical imaging tasks such as tumour segmentation as they account for information variability and image diversity. However, in practice, it is frequent that some modalities are missing in patients' data sources, and there is data imbalance due to varying imaging protocols and image corruption. Rather than re-acquiring all patient modality images as a complete set, it is more feasible to use the patients' existing modalities to synthesise the missing modalities and use this improved data for tumour segmentation. Therefore, we propose a generative adversarial network (GAN) that carries out missing modality synthesis for data completion and tumour segmentation. Our experiments were carried out using the Brain Tumour Image Segmentation Benchmark 2019 (BraTS ’19) dataset and our experiments support that the synthesis of the missing modality benefitted the tumour segmentation results and produced better results compared to other experiments with missing modality. Because of an impending technical disclosure being written, some details about the proposed model has been omitted from this report. Bachelor of Engineering (Computer Science) 2021-04-26T07:27:16Z 2021-04-26T07:27:16Z 2021 Final Year Project (FYP) Rajasekara Pandian Akshaya Muthu (2021). Synthesising missing modalities for multimodal MRI segmentation. Final Year Project (FYP), Nanyang Technological University, Singapore. https://hdl.handle.net/10356/148195 https://hdl.handle.net/10356/148195 en application/pdf Nanyang Technological University
spellingShingle Engineering::Computer science and engineering::Computing methodologies::Artificial intelligence
Rajasekara Pandian Akshaya Muthu
Synthesising missing modalities for multimodal MRI segmentation
title Synthesising missing modalities for multimodal MRI segmentation
title_full Synthesising missing modalities for multimodal MRI segmentation
title_fullStr Synthesising missing modalities for multimodal MRI segmentation
title_full_unstemmed Synthesising missing modalities for multimodal MRI segmentation
title_short Synthesising missing modalities for multimodal MRI segmentation
title_sort synthesising missing modalities for multimodal mri segmentation
topic Engineering::Computer science and engineering::Computing methodologies::Artificial intelligence
url https://hdl.handle.net/10356/148195
work_keys_str_mv AT rajasekarapandianakshayamuthu synthesisingmissingmodalitiesformultimodalmrisegmentation