Glycocalyx breakdown is associated With severe disease and fatal outcome in Plasmodium falciparum malaria

Glycocalyx breakdown is associated With severe disease and fatal outcome in Plasmodium falciparum malaria

Background: Interactions between the endothelium and infected erythrocytes play a major role in the pathogenesis of falciparum malaria, with microvascular dysfunction and parasite sequestration associated with worsening outcomes. The glycocalyx is a carbohydrate-rich layer that lines the endotheliu...

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Bibliographic Details
Main Authors: Yeo, Tsin Wen, Weinberg, J. Brice, Lampah, Daniel A., Kenangalem, Enny, Bush, Peggy, Chen, Youwei, Price, Richard N., Young, Sarah, Zhang, Hao Y., Millington, David, Granger, Donald L., Anstey, Nicholas M.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Plasmodium Falciparum
Severe Malaria
Online Access:https://hdl.handle.net/10356/149019

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