A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia
Biomarkers identified for psychosis might allow for early diagnosis, more accurate prognosis, and tailored individualized interventions. Brain-derived neurotrophic factor (BDNF) is suggested to be a likely candidate biomarker for the diagnosis and treatment evaluation in psychosis. The aims of prese...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Online Access: | https://hdl.handle.net/10356/149212 |
| _version_ | 1811682723591356416 |
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| author | Yee, Jie Yin Lee, Tih-Shih Lee, Jimmy Chee Keong |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Yee, Jie Yin Lee, Tih-Shih Lee, Jimmy Chee Keong |
| author_sort | Yee, Jie Yin |
| collection | NTU |
| description | Biomarkers identified for psychosis might allow for early diagnosis, more accurate prognosis, and tailored individualized interventions. Brain-derived neurotrophic factor (BDNF) is suggested to be a likely candidate biomarker for the diagnosis and treatment evaluation in psychosis. The aims of present study were to examine the levels of serum BDNF in both patients with first-episode psychosis (FEP) and in healthy controls for a year, and to investigate the association between BDNF with symptom severity and remission status. |
| first_indexed | 2024-10-01T04:01:22Z |
| format | Journal Article |
| id | ntu-10356/149212 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:01:22Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1492122021-05-18T07:30:42Z A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia Yee, Jie Yin Lee, Tih-Shih Lee, Jimmy Chee Keong Lee Kong Chian School of Medicine (LKCMedicine) Institute of Mental Health Science::General Psychiatry Brain-derived Neurotrophic Factor First-episode Psychosis Biomarkers identified for psychosis might allow for early diagnosis, more accurate prognosis, and tailored individualized interventions. Brain-derived neurotrophic factor (BDNF) is suggested to be a likely candidate biomarker for the diagnosis and treatment evaluation in psychosis. The aims of present study were to examine the levels of serum BDNF in both patients with first-episode psychosis (FEP) and in healthy controls for a year, and to investigate the association between BDNF with symptom severity and remission status. Ministry of Health (MOH) National Medical Research Council (NMRC) This work was supported by the Singapore Ministry of Health's NationalMedical Research Council under the Centre Grant Programme (NMRC/CG/004/2013) and Transition Award (NMRC/TA/002/2012). 2021-05-18T07:13:42Z 2021-05-18T07:13:42Z 2019 Journal Article Yee, J. Y., Lee, T. & Lee, J. C. K. (2019). A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia. Journal of Clinical Psychopharmacology, 39(6), 639-643. https://dx.doi.org/10.1097/JCP.0000000000001118 0271-0749 https://hdl.handle.net/10356/149212 10.1097/JCP.0000000000001118 31688384 6 39 639 643 en NMRC/CG/004/2013 NMRC/TA/002/2012 Journal of Clinical Psychopharmacology © 2019 Wolters Kluwer Health, Inc. All rights reserved. |
| spellingShingle | Science::General Psychiatry Brain-derived Neurotrophic Factor First-episode Psychosis Yee, Jie Yin Lee, Tih-Shih Lee, Jimmy Chee Keong A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia |
| title | A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia |
| title_full | A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia |
| title_fullStr | A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia |
| title_full_unstemmed | A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia |
| title_short | A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia |
| title_sort | longitudinal study of serum brain derived neurotrophic factor levels in first episode schizophrenia |
| topic | Science::General Psychiatry Brain-derived Neurotrophic Factor First-episode Psychosis |
| url | https://hdl.handle.net/10356/149212 |
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