A short chemically modified dsRNA-Binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structure

A short chemically modified dsRNA-Binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structure

RNAs play critical roles in diverse catalytic and regulatory biological processes and are emerging as important disease biomarkers and therapeutic targets. Thus, developing chemical compounds for targeting any desired RNA structures has great potential in biomedical applications. The viral and cellu...

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Bibliographic Details
Main Authors: Kesy, Julita, Patil, Kiran M., Kumar, Subaschandrabose Rajesh, Shu, Zhiyu, Yong, Hui Yee, Zimmermann, Louis, Ong, Alan Ann Lerk, Toh, Desiree-Faye Kaixin, Krishna, Manchugondanahalli S., Yang, Lixia, Decout, Jean-Luc, Luo, Dahai, Prabakaran, Mookkan, Chen, Gang, Kierzek, Elzbieta
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Chemistry
dbPNA
Influenza
Online Access:https://hdl.handle.net/10356/150015

Internet

https://hdl.handle.net/10356/150015

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