General recognition of U‑G, U‑A, and C‑G pairs by double-stranded RNA-binding PNAs incorporated with an artificial nucleobase

General recognition of U‑G, U‑A, and C‑G pairs by double-stranded RNA-binding PNAs incorporated with an artificial nucleobase

Chemically modified peptide nucleic acids (PNAs) show great promise in the recognition of RNA duplexes by major-groove PNA·RNA–RNA triplex formation. Triplex formation is favored for RNA duplexes with a purine tract within one of the RNA duplex strands, and is severely destabilized if the purine tra...

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Bibliografiska uppgifter
Huvudupphovsmän: Ong, Alan Ann Lerk, Toh, Desiree-Faye Kaixin, Patil, Kiran M., Meng, Zhenyu, Yuan, Zhen, Krishna, Manchugondanahalli S., Devi, Gitali, Haruehanroengra, Phensinee, Lu, Yunpeng, Xia, Kelin, Okamura, Katsutomo, Sheng, Jia, Chen, Gang
Övriga upphovsmän: Interdisciplinary Graduate School (IGS)
Materialtyp: Journal Article
Språk:English
Publicerad: 2021
Ämnen:
Science::Biological sciences
Peptide Nucleic-acids
Triplex-forming Oligonucleotides
Länkar:https://hdl.handle.net/10356/151002

Internet

https://hdl.handle.net/10356/151002

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