A new role for Drosophila Aurora-A in maintaining chromosome integrity

Aurora-A is a conserved mitotic kinase overexpressed in many types of cancer. Growing evidence shows that Aurora-A plays a crucial role in DNA damage response (DDR) although this aspect has been less characterized. We isolated a new aur-A mutation, named aur-A949, in Drosophila, and we showed that i...

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Bibliographic Details
Main Authors: Merigliano, Chiara, Mascolo, Elisa, Cesta, Anthony, Saggio, Isabella, Vernì, Fiammetta
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/151271