Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing
Hyperbolic metamaterials (HMMs) have emerged as a burgeoning field of research over the past few years as their dispersion can be easily engineered in different spectral regions using various material combinations. Even though HMMs have comparatively low optical loss due to a single resonance, the n...
| Main Authors: | , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Online Access: | https://hdl.handle.net/10356/151670 |
| _version_ | 1826109639210565632 |
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| author | Sreekanth, Kandammathe Valiyaveedu Ouyang, Qingling Sreejith, Sivaramapanicker Zeng, Shuwen Wu, Lishu Ilker, Efe Dong, Weiling Mohamed ElKabbash Yu, Ting Lim, Chwee Teck Hinczewski, Michael Strangi, Giuseppe Yong, Ken-Tye Simpson, Robert E. Singh, Ranjan |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Sreekanth, Kandammathe Valiyaveedu Ouyang, Qingling Sreejith, Sivaramapanicker Zeng, Shuwen Wu, Lishu Ilker, Efe Dong, Weiling Mohamed ElKabbash Yu, Ting Lim, Chwee Teck Hinczewski, Michael Strangi, Giuseppe Yong, Ken-Tye Simpson, Robert E. Singh, Ranjan |
| author_sort | Sreekanth, Kandammathe Valiyaveedu |
| collection | NTU |
| description | Hyperbolic metamaterials (HMMs) have emerged as a burgeoning field of research over the past few years as their dispersion can be easily engineered in different spectral regions using various material combinations. Even though HMMs have comparatively low optical loss due to a single resonance, the noble-metal-based HMMs are limited by their strong energy dissipation in metallic layers at visible frequencies. Here, the fabrication of noble-metal-free reconfigurable HMMs for visible photonic applications is experimentally demonstrated. The low-loss and active HMMs are realized by combining titanium nitride (TiN) and stibnite (Sb₂S₃) as the phase change material. A reconfigurable plasmonic biosensor platform based on active Sb₂S₃–TiN HMMs is proposed, and it is shown that significant improvement in sensitivity is possible for small molecule detection at low concentrations. In addition, a plasmonic apta-biosensor based on a hybrid platform of graphene and Sb₂S₃–TiN HMM is developed and the detection and real-time binding of thrombin concentration as low as 1 × 10⁻¹⁵ m are demonstrated. A biosensor operating in the visible range has several advantages including the availability of sources and detectors in this region, and ease of operation particularly for point-of-care applications. |
| first_indexed | 2024-10-01T02:21:32Z |
| format | Journal Article |
| id | ntu-10356/151670 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:21:32Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1516702023-02-28T19:54:54Z Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing Sreekanth, Kandammathe Valiyaveedu Ouyang, Qingling Sreejith, Sivaramapanicker Zeng, Shuwen Wu, Lishu Ilker, Efe Dong, Weiling Mohamed ElKabbash Yu, Ting Lim, Chwee Teck Hinczewski, Michael Strangi, Giuseppe Yong, Ken-Tye Simpson, Robert E. Singh, Ranjan School of Physical and Mathematical Sciences School of Electrical and Electronic Engineering Centre for Disruptive Photonic Technologies (CDPT) The Photonics Institute CNRS International NTU THALES Research Alliances Research Techno Plaza Science::Physics Goos–Hänchen Shift Hyperbolic Metamaterials Hyperbolic metamaterials (HMMs) have emerged as a burgeoning field of research over the past few years as their dispersion can be easily engineered in different spectral regions using various material combinations. Even though HMMs have comparatively low optical loss due to a single resonance, the noble-metal-based HMMs are limited by their strong energy dissipation in metallic layers at visible frequencies. Here, the fabrication of noble-metal-free reconfigurable HMMs for visible photonic applications is experimentally demonstrated. The low-loss and active HMMs are realized by combining titanium nitride (TiN) and stibnite (Sb₂S₃) as the phase change material. A reconfigurable plasmonic biosensor platform based on active Sb₂S₃–TiN HMMs is proposed, and it is shown that significant improvement in sensitivity is possible for small molecule detection at low concentrations. In addition, a plasmonic apta-biosensor based on a hybrid platform of graphene and Sb₂S₃–TiN HMM is developed and the detection and real-time binding of thrombin concentration as low as 1 × 10⁻¹⁵ m are demonstrated. A biosensor operating in the visible range has several advantages including the availability of sources and detectors in this region, and ease of operation particularly for point-of-care applications. Ministry of Education (MOE) Accepted version The authors (K.V.S. and R.S.) acknowledge Singapore Ministry of Education (MOE) (Grant No. MOE2015-T2-2-103) for funding of this research. S.S. and C.T.L. acknowledge support from the NUS-Biomedical Institute for Global Health Research and Technology. We thank Dr. Giorgio Adamo (CDPT, NTU-Singapore) for his support with SEM imaging. 2021-07-22T08:46:10Z 2021-07-22T08:46:10Z 2019 Journal Article Sreekanth, K. V., Ouyang, Q., Sreejith, S., Zeng, S., Wu, L., Ilker, E., Dong, W., Mohamed ElKabbash, Yu, T., Lim, C. T., Hinczewski, M., Strangi, G., Yong, K., Simpson, R. E. & Singh, R. (2019). Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing. Advanced Optical Materials, 7(12), 1900081-. https://dx.doi.org/10.1002/adom.201900081 2195-1071 0000-0002-0254-0938 https://hdl.handle.net/10356/151670 10.1002/adom.201900081 2-s2.0-85064522029 12 7 1900081 en MOE2015-T2-2-103 Advanced Optical Materials 10.21979/N9/JPRKXS This is the peer reviewed version of the following article: Sreekanth, K. V., Ouyang, Q., Sreejith, S., Zeng, S., Wu, L., Ilker, E., Dong, W., Mohamed ElKabbash, Yu, T., Lim, C. T., Hinczewski, M., Strangi, G., Yong, K., Simpson, R. E. & Singh, R. (2019). Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing. Advanced Optical Materials, 7(12), 1900081-, which has been published in final form at https://doi.org/10.1002/adom.201900081. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. application/pdf application/pdf |
| spellingShingle | Science::Physics Goos–Hänchen Shift Hyperbolic Metamaterials Sreekanth, Kandammathe Valiyaveedu Ouyang, Qingling Sreejith, Sivaramapanicker Zeng, Shuwen Wu, Lishu Ilker, Efe Dong, Weiling Mohamed ElKabbash Yu, Ting Lim, Chwee Teck Hinczewski, Michael Strangi, Giuseppe Yong, Ken-Tye Simpson, Robert E. Singh, Ranjan Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing |
| title | Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing |
| title_full | Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing |
| title_fullStr | Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing |
| title_full_unstemmed | Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing |
| title_short | Phase-change-material-based low-loss visible-frequency hyperbolic metamaterials for ultrasensitive label-free biosensing |
| title_sort | phase change material based low loss visible frequency hyperbolic metamaterials for ultrasensitive label free biosensing |
| topic | Science::Physics Goos–Hänchen Shift Hyperbolic Metamaterials |
| url | https://hdl.handle.net/10356/151670 |
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