Methionine is a metabolic dependency of tumor-initiating cells

Methionine is a metabolic dependency of tumor-initiating cells

Understanding cellular metabolism holds immense potential for developing new classes of therapeutics that target metabolic pathways in cancer. Metabolic pathways are altered in bulk neoplastic cells in comparison to normal tissues. However, carcinoma cells within tumors are heterogeneous, and tumor-...

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Bibliographic Details
Main Authors: Wang, Zhenxun, Yip, Lian Yee, Lee, Jane Jia Hui, Wu, Zhengwei, Chew, Hui Yi, Chong, William Pooi Kiat, Teo, Chin Chye, Ang, Heather Yin-Kuan, Peh, Esther Kai Lay, Yuan, Ju, Ma, Siming, Choo, Kimberly Li Shi, Basri, Nurhidayah, Jiang, Xia, Yu, Qiang, Hillmer, Axel M., Lim, Wan Teck, Lim, Tony Kiat Hon, Takano, Angela, Tan, Eng Huat, Tan, Daniel Shao Weng, Ho, Ying Swan, Lim, Bing, Tam, Wai Leong
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
Amino Acid Requirements
Cancer Stem-cells
Online Access:https://hdl.handle.net/10356/151732

Internet

https://hdl.handle.net/10356/151732

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