Regulation of T cell functions by an "ionic checkpoint"
This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the ef...
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Format: | Student Research Poster |
Language: | English |
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Nanyang Technological University
2021
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Online Access: | https://hdl.handle.net/10356/151815 |
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author | Ng, Aik Seng |
author2 | Chandy George Kanianthara |
author_facet | Chandy George Kanianthara Ng, Aik Seng |
author_sort | Ng, Aik Seng |
collection | NTU |
description | This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector
functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award] |
first_indexed | 2024-10-01T06:38:16Z |
format | Student Research Poster |
id | ntu-10356/151815 |
institution | Nanyang Technological University |
language | English |
last_indexed | 2024-10-01T06:38:16Z |
publishDate | 2021 |
publisher | Nanyang Technological University |
record_format | dspace |
spelling | ntu-10356/1518152021-07-04T20:11:30Z Regulation of T cell functions by an "ionic checkpoint" Ng, Aik Seng Chandy George Kanianthara Navin Kumar Verma School of Biological Sciences nkverma@ntu.edu.sg, gchandy@ntu.edu.sg Science::Biological sciences This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award] 2021-07-02T05:21:22Z 2021-07-02T05:21:22Z 2019 Student Research Poster Ng, A. S. (2019). Regulation of T cell functions by an "ionic checkpoint". Student Research Poster, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/151815 https://hdl.handle.net/10356/151815 en LKCM18005 © 2019 The Author(s). application/pdf Nanyang Technological University |
spellingShingle | Science::Biological sciences Ng, Aik Seng Regulation of T cell functions by an "ionic checkpoint" |
title | Regulation of T cell functions by an "ionic checkpoint" |
title_full | Regulation of T cell functions by an "ionic checkpoint" |
title_fullStr | Regulation of T cell functions by an "ionic checkpoint" |
title_full_unstemmed | Regulation of T cell functions by an "ionic checkpoint" |
title_short | Regulation of T cell functions by an "ionic checkpoint" |
title_sort | regulation of t cell functions by an ionic checkpoint |
topic | Science::Biological sciences |
url | https://hdl.handle.net/10356/151815 |
work_keys_str_mv | AT ngaikseng regulationoftcellfunctionsbyanioniccheckpoint |