Regulation of T cell functions by an "ionic checkpoint"

This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the ef...

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Bibliographic Details
Main Author: Ng, Aik Seng
Other Authors: Chandy George Kanianthara
Format: Student Research Poster
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/151815
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author Ng, Aik Seng
author2 Chandy George Kanianthara
author_facet Chandy George Kanianthara
Ng, Aik Seng
author_sort Ng, Aik Seng
collection NTU
description This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award]
first_indexed 2024-10-01T06:38:16Z
format Student Research Poster
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institution Nanyang Technological University
language English
last_indexed 2024-10-01T06:38:16Z
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publisher Nanyang Technological University
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spelling ntu-10356/1518152021-07-04T20:11:30Z Regulation of T cell functions by an "ionic checkpoint" Ng, Aik Seng Chandy George Kanianthara Navin Kumar Verma School of Biological Sciences nkverma@ntu.edu.sg, gchandy@ntu.edu.sg Science::Biological sciences This study advances the fundamental understandings of ionic-checkpoint and its role in regulating immune functions. Pharmacological activators are able to rescue T cells of the high K+-mediated suppression and restore T cell effector functions. Our study suggests a new approach for improving the effectiveness of cancer immunotherapies. [1st Award] 2021-07-02T05:21:22Z 2021-07-02T05:21:22Z 2019 Student Research Poster Ng, A. S. (2019). Regulation of T cell functions by an "ionic checkpoint". Student Research Poster, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/151815 https://hdl.handle.net/10356/151815 en LKCM18005 © 2019 The Author(s). application/pdf Nanyang Technological University
spellingShingle Science::Biological sciences
Ng, Aik Seng
Regulation of T cell functions by an "ionic checkpoint"
title Regulation of T cell functions by an "ionic checkpoint"
title_full Regulation of T cell functions by an "ionic checkpoint"
title_fullStr Regulation of T cell functions by an "ionic checkpoint"
title_full_unstemmed Regulation of T cell functions by an "ionic checkpoint"
title_short Regulation of T cell functions by an "ionic checkpoint"
title_sort regulation of t cell functions by an ionic checkpoint
topic Science::Biological sciences
url https://hdl.handle.net/10356/151815
work_keys_str_mv AT ngaikseng regulationoftcellfunctionsbyanioniccheckpoint