3D multi-modality medical image registration with GAN-based synthetic image augmentation

Medical image registration is a crucial yet challenging task in medical image analysis and processing. we propose an end-to-end unsupervised multi-modality deformable image registration network with CycleGAN augmentation. The proposed method is designed for intra-subject brain MRI-CT registration. T...

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Bibliographic Details
Main Author: Guo, Zhiwei
Other Authors: Jagath C Rajapakse
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/152248
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author Guo, Zhiwei
author2 Jagath C Rajapakse
author_facet Jagath C Rajapakse
Guo, Zhiwei
author_sort Guo, Zhiwei
collection NTU
description Medical image registration is a crucial yet challenging task in medical image analysis and processing. we propose an end-to-end unsupervised multi-modality deformable image registration network with CycleGAN augmentation. The proposed method is designed for intra-subject brain MRI-CT registration. The registration network can be divided into two stage. First, it generates a synthetic CT image from its corresponding MRI image by using CycleGAN. Second, by feeding the synthetic CT (sCT) and original CT into an unsupervised registration network, the deformation field to align the sCT and CT image is obtained, which is also the deformation field applied to the MRI image to align with CT image. Compared with state-of-art unsupervised registration method, instead of calculating a single mono-modality image similarity on CT and warped sCT, we also include a mutual information multi-modality image similarity on CT and warped MRI. We demonstrated that our proposed method outperforms both current state-of-the-art registration algorithm and existing registration tools. Because of an impending Technical Disclosure, some details of methodology have been omitted in this report.
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spelling ntu-10356/1522482021-08-02T02:30:07Z 3D multi-modality medical image registration with GAN-based synthetic image augmentation Guo, Zhiwei Jagath C Rajapakse School of Computer Science and Engineering ASJagath@ntu.edu.sg Engineering::Computer science and engineering Medical image registration is a crucial yet challenging task in medical image analysis and processing. we propose an end-to-end unsupervised multi-modality deformable image registration network with CycleGAN augmentation. The proposed method is designed for intra-subject brain MRI-CT registration. The registration network can be divided into two stage. First, it generates a synthetic CT image from its corresponding MRI image by using CycleGAN. Second, by feeding the synthetic CT (sCT) and original CT into an unsupervised registration network, the deformation field to align the sCT and CT image is obtained, which is also the deformation field applied to the MRI image to align with CT image. Compared with state-of-art unsupervised registration method, instead of calculating a single mono-modality image similarity on CT and warped sCT, we also include a mutual information multi-modality image similarity on CT and warped MRI. We demonstrated that our proposed method outperforms both current state-of-the-art registration algorithm and existing registration tools. Because of an impending Technical Disclosure, some details of methodology have been omitted in this report. Bachelor of Engineering (Computer Science) 2021-07-26T01:27:54Z 2021-07-26T01:27:54Z 2021 Final Year Project (FYP) Guo, Z. (2021). 3D multi-modality medical image registration with GAN-based synthetic image augmentation. Final Year Project (FYP), Nanyang Technological University, Singapore. https://hdl.handle.net/10356/152248 https://hdl.handle.net/10356/152248 en application/pdf Nanyang Technological University
spellingShingle Engineering::Computer science and engineering
Guo, Zhiwei
3D multi-modality medical image registration with GAN-based synthetic image augmentation
title 3D multi-modality medical image registration with GAN-based synthetic image augmentation
title_full 3D multi-modality medical image registration with GAN-based synthetic image augmentation
title_fullStr 3D multi-modality medical image registration with GAN-based synthetic image augmentation
title_full_unstemmed 3D multi-modality medical image registration with GAN-based synthetic image augmentation
title_short 3D multi-modality medical image registration with GAN-based synthetic image augmentation
title_sort 3d multi modality medical image registration with gan based synthetic image augmentation
topic Engineering::Computer science and engineering
url https://hdl.handle.net/10356/152248
work_keys_str_mv AT guozhiwei 3dmultimodalitymedicalimageregistrationwithganbasedsyntheticimageaugmentation