Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships
Humans are evolutionary-driven to adult mating and conceive social expectations on the quality of their affiliations. The genetic susceptibility to adverse environments in critical periods can alter close relationships. The current research investigates how the promoter region of the Serotonin Trans...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/152804 |
| _version_ | 1811679397160157184 |
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| author | Bonassi, Andrea Cataldo, Ilaria Gabrieli, Giulio Lepri, Bruno Esposito, Gianluca |
| author2 | School of Social Sciences |
| author_facet | School of Social Sciences Bonassi, Andrea Cataldo, Ilaria Gabrieli, Giulio Lepri, Bruno Esposito, Gianluca |
| author_sort | Bonassi, Andrea |
| collection | NTU |
| description | Humans are evolutionary-driven to adult mating and conceive social expectations on the quality of their affiliations. The genetic susceptibility to adverse environments in critical periods can alter close relationships. The current research investigates how the promoter region of the Serotonin Transporter Gene (5-HTTLPR) and perceived caregiving behavior in childhood could influence the social expectations on close adult relationships. For this purpose, 5-HTTLPR data was collected from the buccal mucosa of 65 Italian individuals (33 males). The participants filled (a) the Parental Bonding Instrument (PBI) to provide the levels of care and overprotection from mother and father, and (b) the Experience in Close Relationships-Revised (ECR-R) to report the social expectations on the intimate relationship assessed in terms of anxiety and avoidance from the partner. An interaction effect between 5-HTTLPR and PBI dimensions on the ECR-R scores was hypothesized. Results confirmed that the interplay between the genetic groups and history of maternal overprotection predicted avoidance experienced in romantic relationships in adulthood. Moreover, both adult anxiety and avoidance felt in an intimate relationship were found to covary as a function of maternal overprotection. The present work proposes further evidence of the genetic and parental mechanisms regulating social expectations involved in close relationships. |
| first_indexed | 2024-10-01T03:08:30Z |
| format | Journal Article |
| id | ntu-10356/152804 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:08:30Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1528042023-03-05T15:31:21Z Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships Bonassi, Andrea Cataldo, Ilaria Gabrieli, Giulio Lepri, Bruno Esposito, Gianluca School of Social Sciences Lee Kong Chian School of Medicine (LKCMedicine) Social sciences::Psychology Gene Environment Serotonin Transporter Gene Humans are evolutionary-driven to adult mating and conceive social expectations on the quality of their affiliations. The genetic susceptibility to adverse environments in critical periods can alter close relationships. The current research investigates how the promoter region of the Serotonin Transporter Gene (5-HTTLPR) and perceived caregiving behavior in childhood could influence the social expectations on close adult relationships. For this purpose, 5-HTTLPR data was collected from the buccal mucosa of 65 Italian individuals (33 males). The participants filled (a) the Parental Bonding Instrument (PBI) to provide the levels of care and overprotection from mother and father, and (b) the Experience in Close Relationships-Revised (ECR-R) to report the social expectations on the intimate relationship assessed in terms of anxiety and avoidance from the partner. An interaction effect between 5-HTTLPR and PBI dimensions on the ECR-R scores was hypothesized. Results confirmed that the interplay between the genetic groups and history of maternal overprotection predicted avoidance experienced in romantic relationships in adulthood. Moreover, both adult anxiety and avoidance felt in an intimate relationship were found to covary as a function of maternal overprotection. The present work proposes further evidence of the genetic and parental mechanisms regulating social expectations involved in close relationships. Ministry of Education (MOE) Nanyang Technological University Published version This research was supported by grants from the NAP SUG (M4081597, 2015-2021) and the Ministry of Education, Singapore, under its Academic Research Fund Tier 1 (RG55/18) to G.E. 2021-10-06T08:27:57Z 2021-10-06T08:27:57Z 2021 Journal Article Bonassi, A., Cataldo, I., Gabrieli, G., Lepri, B. & Esposito, G. (2021). Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships. Brain Sciences, 11(9), 1123-. https://dx.doi.org/10.3390/brainsci11091123 2076-3425 https://hdl.handle.net/10356/152804 10.3390/brainsci11091123 34573145 2-s2.0-85114036839 9 11 1123 en M4081597 RG55/18 Brain Sciences 10.21979/N9/SZNMRI © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). application/pdf |
| spellingShingle | Social sciences::Psychology Gene Environment Serotonin Transporter Gene Bonassi, Andrea Cataldo, Ilaria Gabrieli, Giulio Lepri, Bruno Esposito, Gianluca Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| title | Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| title_full | Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| title_fullStr | Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| title_full_unstemmed | Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| title_short | Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| title_sort | serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships |
| topic | Social sciences::Psychology Gene Environment Serotonin Transporter Gene |
| url | https://hdl.handle.net/10356/152804 |
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