Alternative splicing in human myeloid cell differentiation and leukaemia
Dysregulation of alternative splicing (AS) has been implicated in aberrant cell function, resulting in diseases such as acute myeloid leukaemia (AML). It was found that myeloid cell differentiation was impaired due to mutations and altered expression levels of splicing factors (SFs). Preliminary dat...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/153292 |