Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown in international studies to be effective and well-tolerated in virologically suppressed in...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Online Access: | https://hdl.handle.net/10356/153553 |
| _version_ | 1811682886416334848 |
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| author | Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S. |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S. |
| author_sort | Lim, Z. C. |
| collection | NTU |
| description | The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown in international studies to be effective and well-tolerated in virologically suppressed individuals. This study evaluated the effectiveness and safety of switching to ABC/3TC + RPV as maintenance therapy in virologically suppressed HIV-1 infected individuals in Singapore. |
| first_indexed | 2024-10-01T04:03:58Z |
| format | Journal Article |
| id | ntu-10356/153553 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:03:58Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1535532023-03-05T16:48:40Z Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S. Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Maintenance Switch Therapy The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown in international studies to be effective and well-tolerated in virologically suppressed individuals. This study evaluated the effectiveness and safety of switching to ABC/3TC + RPV as maintenance therapy in virologically suppressed HIV-1 infected individuals in Singapore. Published version 2021-12-08T05:08:49Z 2021-12-08T05:08:49Z 2021 Journal Article Lim, Z. C., Hoo, G. S., Ang, J. H., Teng, C. B., Ang, L. W., Lee, C. C., Leo, Y. S., Law, H. L., Ng, O. T. & Wong, C. S. (2021). Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS). AIDS Research and Therapy, 18(1), 80-. https://dx.doi.org/10.1186/s12981-021-00402-7 1742-6405 https://hdl.handle.net/10356/153553 10.1186/s12981-021-00402-7 34724931 2-s2.0-85118584075 1 18 80 en AIDS Research and Therapy © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. application/pdf |
| spellingShingle | Science::Medicine Maintenance Switch Therapy Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S. Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) |
| title | Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) |
| title_full | Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) |
| title_fullStr | Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) |
| title_full_unstemmed | Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) |
| title_short | Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) |
| title_sort | safety and effectiveness of switching to abacavir lamivudine plus rilpivirine for maintenance therapy in virologically suppressed hiv 1 individuals in singapore seals |
| topic | Science::Medicine Maintenance Switch Therapy |
| url | https://hdl.handle.net/10356/153553 |
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