TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus

TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus

The pathogenetic mechanisms underlying neuronal death and dysfunction in Alzheimer's disease (AD) remain unclear. However, chronic neuroinflammation has been implicated in stimulating or exacerbating neuronal damage. The tumor necrosis factor (TNF) superfamily of cytokines are involved in many...

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Bibliographic Details
Main Authors: Jayaraman, Anusha, Htike, Thein Than, James, Rachel, Picon, Carmen, Reynolds, Richard
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Necroptosis
Alzheimer’s Disease
Online Access:https://hdl.handle.net/10356/153812

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