Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications
Sporopollenin sporoderm microcapsules (S-SMCs) are readily extracted from plant pollen grains and provide a renewable, biocompatible source of robust microparticles for a wide range of potential applications. While the lipidic/aromatic sporopollenin copolymer surface results in a predominantly hydro...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/154188 |
| _version_ | 1811690894820114432 |
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| author | Tan, Ee-Lin Potroz, Michael G. Ferracci, Gaia Wang, Lili Jackman, J. A. Cho, Nam-Joon |
| author2 | School of Materials Science and Engineering |
| author_facet | School of Materials Science and Engineering Tan, Ee-Lin Potroz, Michael G. Ferracci, Gaia Wang, Lili Jackman, J. A. Cho, Nam-Joon |
| author_sort | Tan, Ee-Lin |
| collection | NTU |
| description | Sporopollenin sporoderm microcapsules (S-SMCs) are readily extracted from plant pollen grains and provide a renewable, biocompatible source of robust microparticles for a wide range of potential applications. While the lipidic/aromatic sporopollenin copolymer surface results in a predominantly hydrophobic interface, herein, we demonstrate how ultraviolet/ozone (UV-O) light-induced tuning of S-SMC interfacial properties enables production of hydrophobic to superhydrophilic microparticles, along with programmable function for colloidal science and cellular applications. In oil/water systems, stable Pickering emulsions are achieved using S-SMCs with short duration UV-O treatment, while incorporation of superhydrophilic S-SMCs into oil/water systems provides a novel means to produce, and isolate, fully oil-loaded microparticles. Furthermore, it is shown that human cells adhere to S-SMCs acting as tissue seeds, with the controllable formation of either 3D cell spheroids or network structures. Collectively, our findings demonstrate that light-induced modification of S-SMCs has broad implications across colloidal science, microencapsulation, drug delivery, and cellular applications. |
| first_indexed | 2024-10-01T06:11:15Z |
| format | Journal Article |
| id | ntu-10356/154188 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:11:15Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1541882021-12-16T01:27:03Z Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications Tan, Ee-Lin Potroz, Michael G. Ferracci, Gaia Wang, Lili Jackman, J. A. Cho, Nam-Joon School of Materials Science and Engineering Engineering::Materials Biomaterials Biomimetics Sporopollenin sporoderm microcapsules (S-SMCs) are readily extracted from plant pollen grains and provide a renewable, biocompatible source of robust microparticles for a wide range of potential applications. While the lipidic/aromatic sporopollenin copolymer surface results in a predominantly hydrophobic interface, herein, we demonstrate how ultraviolet/ozone (UV-O) light-induced tuning of S-SMC interfacial properties enables production of hydrophobic to superhydrophilic microparticles, along with programmable function for colloidal science and cellular applications. In oil/water systems, stable Pickering emulsions are achieved using S-SMCs with short duration UV-O treatment, while incorporation of superhydrophilic S-SMCs into oil/water systems provides a novel means to produce, and isolate, fully oil-loaded microparticles. Furthermore, it is shown that human cells adhere to S-SMCs acting as tissue seeds, with the controllable formation of either 3D cell spheroids or network structures. Collectively, our findings demonstrate that light-induced modification of S-SMCs has broad implications across colloidal science, microencapsulation, drug delivery, and cellular applications. Nanyang Technological University National Research Foundation (NRF) The authors acknowledge technical support from Ms. Ekaterina Stonkevitch. This research was supported by the Creative Materials Discovery Programthroughthe NationalResearchFoundationof Korea (NRF)funded by the Ministry of Science, ICT, and Future Planning (NRF- 2016M3D1A1024098). This work was also supported by the Competitive Research Programme (NRF-CRP10-2012-07) ofthe National Research Foundation of Singapore (NRF). The research was also supported by a Start-Up Grant (SUG) from Nanyang Technological University (M4080751.070). Many thanks are due to Dr. Y. N. Liang from the Nanyang Environment & Water Research Institute (NEWRI) for collection of the XPS data and to Dr. S. Pedersen for assistance with utilizing R-Code for data analysis. 2021-12-16T01:27:03Z 2021-12-16T01:27:03Z 2020 Journal Article Tan, E., Potroz, M. G., Ferracci, G., Wang, L., Jackman, J. A. & Cho, N. (2020). Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications. Applied Materials Today, 18, 100525-. https://dx.doi.org/10.1016/j.apmt.2019.100525 2352-9407 https://hdl.handle.net/10356/154188 10.1016/j.apmt.2019.100525 2-s2.0-85076534183 18 100525 en NRF-CRP10-2012-07 M4080751.070 Applied Materials Today © 2019 Elsevier Ltd. All rights reserved |
| spellingShingle | Engineering::Materials Biomaterials Biomimetics Tan, Ee-Lin Potroz, Michael G. Ferracci, Gaia Wang, Lili Jackman, J. A. Cho, Nam-Joon Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications |
| title | Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications |
| title_full | Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications |
| title_fullStr | Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications |
| title_full_unstemmed | Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications |
| title_short | Hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio-composite applications |
| title_sort | hydrophobic to superhydrophilic tuning of multifunctional sporopollenin for microcapsule and bio composite applications |
| topic | Engineering::Materials Biomaterials Biomimetics |
| url | https://hdl.handle.net/10356/154188 |
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