Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein

Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein

The stringent response, regulated by the bifunctional (p)ppGpp synthetase/hydrolase Rel in mycobacteria, is critical for long-term survival of the drug-tolerant dormant state of Mycobacterium tuberculosis. During amino acid starvation, MtRel senses a drop in amino acid concentration and synthesizes...

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Bibliografiske detaljer
Main Authors: Shin, Joon, Singal, Bharti, Manimekalai, Malathy Sony Subramanian, Wei Chen, Ming, Ragunathan, Priya, Grüber, Gerhard
Andre forfattere: School of Biological Sciences
Format: Journal Article
Sprog:English
Udgivet: 2021
Fag:
Science::Biological sciences
ACT Domain
Mycobacterium tuberculosis
Online adgang:https://hdl.handle.net/10356/154271

Internet

https://hdl.handle.net/10356/154271

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