Biological conversion of sulfamethoxazole in an autotrophic denitrification system
Sulfamethoxazole (SMX) is a common antibiotic prescribed for treating infections, which is frequently detected in the effluent of conventional wastewater treatment plants (WWTPs). Its degradation and conversion in a laboratory-scale sulfur-based autotrophic denitrification reactor were for the first...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/154391 |
| _version_ | 1811685521222533120 |
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| author | Zhang, Liang Sun, Faqian Wu, Dan Yan, Wangwang Zhou, Yan |
| author2 | School of Civil and Environmental Engineering |
| author_facet | School of Civil and Environmental Engineering Zhang, Liang Sun, Faqian Wu, Dan Yan, Wangwang Zhou, Yan |
| author_sort | Zhang, Liang |
| collection | NTU |
| description | Sulfamethoxazole (SMX) is a common antibiotic prescribed for treating infections, which is frequently detected in the effluent of conventional wastewater treatment plants (WWTPs). Its degradation and conversion in a laboratory-scale sulfur-based autotrophic denitrification reactor were for the first time investigated through long-term reactor operation and short-term batch experiments. Co-metabolism of SMX and nitrate by autotrophic denitrifiers was observed in this study. The specific SMX removal rate was 3.7 ± 1.4 μg/g SS-d, which was higher than those reported in conventional wastewater treatment processes. The removal of SMX by the enriched denitrifying sludge was mainly attributed to biodegradation. Four transformation products (three known with structures and one with unknown structure) were identified, of which the structures of the two transformation products (TPs) were altered in the isoxazole ring. Additionally, the presence of SMX significantly shaped the microbial community structures, leading to the dominant denitrifier shifting from Sulfuritalea to Sulfurimonas to maintain the stability of system. Collectively, the sulfur-based autotrophic denitrification process could effectively remove SMX in addition to efficient nitrate removal, and further polish the effluent from conventional WWTPs. |
| first_indexed | 2024-10-01T04:45:50Z |
| format | Journal Article |
| id | ntu-10356/154391 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:45:50Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1543912021-12-20T08:58:34Z Biological conversion of sulfamethoxazole in an autotrophic denitrification system Zhang, Liang Sun, Faqian Wu, Dan Yan, Wangwang Zhou, Yan School of Civil and Environmental Engineering Nanyang Environment and Water Research Institute Advanced Environmental Biotechnology Centre (AEBC) Engineering::Environmental engineering Sulfamethoxazole (SMX) Removal Biodegradation Sulfamethoxazole (SMX) is a common antibiotic prescribed for treating infections, which is frequently detected in the effluent of conventional wastewater treatment plants (WWTPs). Its degradation and conversion in a laboratory-scale sulfur-based autotrophic denitrification reactor were for the first time investigated through long-term reactor operation and short-term batch experiments. Co-metabolism of SMX and nitrate by autotrophic denitrifiers was observed in this study. The specific SMX removal rate was 3.7 ± 1.4 μg/g SS-d, which was higher than those reported in conventional wastewater treatment processes. The removal of SMX by the enriched denitrifying sludge was mainly attributed to biodegradation. Four transformation products (three known with structures and one with unknown structure) were identified, of which the structures of the two transformation products (TPs) were altered in the isoxazole ring. Additionally, the presence of SMX significantly shaped the microbial community structures, leading to the dominant denitrifier shifting from Sulfuritalea to Sulfurimonas to maintain the stability of system. Collectively, the sulfur-based autotrophic denitrification process could effectively remove SMX in addition to efficient nitrate removal, and further polish the effluent from conventional WWTPs. Nanyang Technological University The authors acknowledge the financial support of Advanced Environmental Biotechnology Centre, Nanyang Environment and Water Research Institute (NEWRI), Nanyang Technological Univer- sity. 2021-12-20T08:58:34Z 2021-12-20T08:58:34Z 2020 Journal Article Zhang, L., Sun, F., Wu, D., Yan, W. & Zhou, Y. (2020). Biological conversion of sulfamethoxazole in an autotrophic denitrification system. Water Research, 185, 116156-. https://dx.doi.org/10.1016/j.watres.2020.116156 0043-1354 https://hdl.handle.net/10356/154391 10.1016/j.watres.2020.116156 33086460 2-s2.0-85089675037 185 116156 en Water Research © 2020 Elsevier Ltd. All rights reserved. |
| spellingShingle | Engineering::Environmental engineering Sulfamethoxazole (SMX) Removal Biodegradation Zhang, Liang Sun, Faqian Wu, Dan Yan, Wangwang Zhou, Yan Biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| title | Biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| title_full | Biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| title_fullStr | Biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| title_full_unstemmed | Biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| title_short | Biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| title_sort | biological conversion of sulfamethoxazole in an autotrophic denitrification system |
| topic | Engineering::Environmental engineering Sulfamethoxazole (SMX) Removal Biodegradation |
| url | https://hdl.handle.net/10356/154391 |
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