In vitro reconstitution and characterisation of structural and dynamic properties of telomeric chromatin
Telomeres, the ends of all linear chromosomes, serve to protect and maintain chromosomal integrity by shielding against unwanted DNA damage responses. The mammalian telomere comprises a repetitive DNA sequence of TTAGGG that is densely packed as nucleosomes with a short NRL of ~157 bp. Despite the i...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2022
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| Online Access: | https://hdl.handle.net/10356/154608 |